How much is the bus ticket from St. Louis to San Antonio?

The cheapest bus tickets from St. Louis to San Antonio start from $110. The average price for this route is around $166. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from St. Louis to San Antonio?

The average bus trip duration from St. Louis to San Antonio is 23h 45m, covering a distance of 790 miles (1274 km). The quickest bus can get you there in 23h 45m and is operated by Greyhound .

Which bus companies service the St. Louis to San Antonio route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from St. Louis to San Antonio?

The earliest bus departs from St. Louis to San Antonio at 1:00am. And the latest bus departs at 4:30pm.

What are the CO₂ emissions for the bus trip from St. Louis to San Antonio?

A bus trip from St. Louis to San Antonio generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from St. Louis to San Antonio?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from St. Louis to San Antonio?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from St. Louis to San Antonio?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from St. Louis to San Antonio?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus St. Louis to San Antonio from $123 | Refundable Tickets

Next bus departures

Next departures for St. Louis to San Antonio on December 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Gateway Station	1d 6h	11:25pm	Pearl District	Cheapest
FlixBus + Greyhound Lines, Inc. + Valley Transit	Bus	4:00pm	Gateway Station	20h 55m	12:55pm	San Antonio Bus Station	Fastest
Greyhound Lines, Inc. + Valley Transit	Bus	4:30pm	Gateway Station	1d 1h	5:35pm	San Antonio Bus Station	No tags

Next departures for St. Louis to San Antonio on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Gateway Station	1d 6h	11:25pm	Pearl District	Cheapest
FlixBus + Greyhound Lines, Inc. + Valley Transit	Bus	4:00pm	Gateway Station	20h 55m	12:55pm	San Antonio Bus Station	Fastest
Greyhound Lines, Inc. + Greyhound Lines Mexico	Bus	1:20am	Gateway Station	22h 30m	11:50pm	San Antonio Bus Station	No tags
Greyhound Lines, Inc. + Valley Transit	Bus	4:30pm	Gateway Station	1d 1h	5:35pm	San Antonio Bus Station	No tags
	Bus	1:30am	Gateway Station	23h 45m	1:15am	San Antonio Bus Station	No tags

Next departures for St. Louis to San Antonio on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc. + Valley Transit	Bus	4:00pm	Gateway Station	20h 55m	12:55pm	San Antonio Bus Station	CheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico	Bus	1:20am	Gateway Station	22h 30m	11:50pm	San Antonio Bus Station	No tags
Greyhound Lines, Inc. + Valley Transit	Bus	4:30pm	Gateway Station	1d 1h	5:35pm	San Antonio Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Gateway Station	1d 6h	11:25pm	Pearl District	No tags
	Bus	1:30am	Gateway Station	23h 45m	1:15am	San Antonio Bus Station	No tags

Last refresh of the prices: Yesterday at 5:38 PM CST.

Compare 2 ways to go from St. Louis to San Antonio

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 23 hours 45 minutes and with fares starting at just $110, it presents an excellent value for a comfortable ride.

5bus per day

23h 45mAverage Duration

790 milesDistance

32kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$110 - $401	Average Duration23h 45m	CO₂ emissions 32kg CO₂e
Train	Average Price$112 - $276	Average Duration1d 2h	CO₂ emissions 116kg CO₂e

Where are the popular stops in St. Louis and San Antonio?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in San Antonio

A
San Antonio Bus Station
500 N St Mary's St, San Antonio, TX 78205, USA
Visit page
B
Tornado I-35
7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
Visit page
C
San Antonio, TX
165 Bowie St, San Antonio, 78205
Visit page
D
4407 S PanAm Expy #101
4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Visit page

Compare bus companies

Greyhound

3.5/587,413 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,517 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from St. Louis to San Antonio, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from St. Louis to San Antonio?
The cheapest bus tickets from St. Louis to San Antonio start from $110. The average price for this route is around $166. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to San Antonio?
The average bus trip duration from St. Louis to San Antonio is 23h 45m, covering a distance of 790 miles (1274 km). The quickest bus can get you there in 23h 45m and is operated by Greyhound.
Which bus companies service the St. Louis to San Antonio route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from St. Louis to San Antonio?
The earliest bus departs from St. Louis to San Antonio at 1:00am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to San Antonio?
A bus trip from St. Louis to San Antonio generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to San Antonio?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from St. Louis to San Antonio?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from St. Louis to San Antonio?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to San Antonio?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/02

$231

12/03

$220

Today

$228

12/05

$150

12/06

$134

12/07

$126

12/08

$137

12/09

$133

The cheapest trip from St. Louis to San Antonio, US was searched and found on Dec 7, 2025 with a price of $126

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Antonio, US, as early as possible.

You can expect to pay from $126 to $231 for a bus ticket from St. Louis to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-12-07.