Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Charlotte (Freedom Dr) | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
 | Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
| Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
| Bus | Gateway Station | Charlotte Bus Station | No tags |
Last refresh of the prices: Today at 1:52 PM CST.
Compare 2 ways to go from St. Louis to Charlotte
Among the sustainable travel choices, the bus stands out as the good way to reach Charlotte. The journey takes about 18 hours 30 minutes and with fares starting at just $109, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Charlotte?
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
Compare bus companies
Frequently asked questions about traveling from St. Louis to Charlotte, NC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Charlotte?
The cheapest bus tickets from St. Louis to Charlotte start from $109. The average price for this route is around $142. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Charlotte?
The average bus trip duration from St. Louis to Charlotte is 18h 30m, covering a distance of 564 miles (909 km). The quickest bus can get you there in 17h 30m and is operated by FlixBus.
Which bus companies service the St. Louis to Charlotte route?
What is the earliest and latest departure time for the bus from St. Louis to Charlotte?
The earliest bus departs from St. Louis to Charlotte at 1:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Charlotte?
A bus trip from St. Louis to Charlotte generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to Charlotte?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from St. Louis to Charlotte?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from St. Louis to Charlotte?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Charlotte?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Charlotte, NC was searched and found on Dec 4, 2025 with a price of $98To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Charlotte, NC, as early as possible.
You can expect to pay from $98 to $226 for a bus ticket from St. Louis to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $116 which is on 2025-12-08.
What's the cheapest way to go from St. Louis to Charlotte, NC?
The bus is the cheapest travel choice for this destination
