Next departures for South Bend to Syracuse on November 24
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South Bend
Syracuse (Regional Transportation Center)
CheapestFastest
Next departures for South Bend to Syracuse on November 26
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South Bend
Syracuse (Regional Transportation Center)
CheapestFastest
Next departures for South Bend to Syracuse on November 27
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South Bend
Syracuse (Regional Transportation Center)
CheapestFastest
Next departures for South Bend to Syracuse on November 29
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South Bend
Syracuse (Regional Transportation Center)
CheapestFastest
Last refresh of the prices: Yesterday at 12:20 AM EST.
Compare 2 ways to go from South Bend to Syracuse
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Syracuse. The journey takes about 11 hours 29 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from South Bend to Syracuse, US by bus
What is the travel distance from South Bend to Syracuse?
The distance separating South Bend and Syracuse is 523 miles (844 km).
What are the best sights and things to do in Syracuse?
Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are WonderWorks, The Great New York State Fair, Carrier Dome, Erie Canal Museum and Onondaga Historical Association Museum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/22
$128
11/23
$151
Today
$214
11/25
$177
11/26
$150
11/27
$124
11/28
No data
11/29
$504
The cheapest trip from South Bend to Syracuse, US was searched and found on Nov 27, 2025 with a price of $124
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from South Bend to Syracuse, US, as early as possible.
You can expect to pay from $124 to $504 for a bus ticket from South Bend to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $124 which is on 2025-11-27.