Bus Tickets from Prague to Madrid

Previously seen trips

Next departures for Prague to Madrid on October 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Prague (Na Knížecí)
Madrid (South)No tags
FlixBus
Tomíčkova
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
FlixBus
Prague (Central Bus Station Florenc)
Madrid (South)No tags
FlixBus
Černý Most
Madrid (South)No tags
FlixBus
Prague (Central Bus Station Florenc)
Madrid (South)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Prague to Madrid: Trip Overview

Average ticket price$245
Average bus trip duration1d 15h
Number of daily buses28
Earliest bus departure6:50am
Distance1094 miles (1764 km)
Latest bus departure11:05pm

Prague to Madrid Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Prague to Madrid.

We make sure you can find a bus service from Prague to Madrid from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Prague to Madrid, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Prague - Madrid

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/30
$164
10/01
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Today
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10/03
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10/04
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10/05
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10/06
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10/07
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busbud logoThe cheapest trip from Prague to Madrid was searched and found on Sep 30, 2025 with a price of $164

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Madrid, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Prague to Madrid but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Prague to Madrid, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Prague to Madrid that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Prague to Madrid.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Prague by bus?

Bus from Madrid to Prague

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