Bus Tickets from Prague to Frankfurt am Main

Next departures

Next departures for Prague to Frankfurt am Main on October 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Prague (Main Station - parking)
Frankfurt HbfCheapest
RegioJet
Florenc
Frankfurt - Main bus stationFastest
Flixbus
Prague (Central Bus Station Florenc)
FRA Frankfurt airportNo tags
Flixbus
Prague (Central Bus Station Florenc)
FRA Frankfurt airportNo tags
Flixbus
Prague (Central Bus Station Florenc)
FRA Frankfurt airportNo tags

Last refresh of the prices: Today at 3:13 PM CEST.

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Compare 3 ways to go from Prague to Frankfurt am Main.

Bus
Average Price$23 - $148Average Duration8h 40m
10kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$32 - $269Average Duration8h 8m
10kg CO₂e5 out of 5 stars
Carpool
Average Price$30 - $40Average Duration5h 10m
17kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Prague to Frankfurt am Main

Among the sustainable travel choices, the carpool stands out as the good way to reach Frankfurt am Main. The journey takes about 5 hours 10 minutes and with fares starting at just $30, it presents an excellent value for a comfortable ride.

1carpool per day
5h 10mAverage Duration
$30Cheapest ticket
17kgCO₂ emissions

Bus Prague to Frankfurt am Main: Trip Overview

Average ticket price$40
Average bus trip duration8h 40m
Number of daily buses29
Earliest bus departure3:30am
Distance260 miles (418 km)
Latest bus departure11:50pm

Prague to Frankfurt am Main Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Prague to Frankfurt am Main.

We make it our job to connect you with the most dependable bus companies that cover bus service from Prague to Frankfurt am Main.

Whether it is cheap bus tickets or more luxurious buses going to Frankfurt am Main from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Prague - Frankfurt am Main

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/28
$50
09/29
$45
Today
$40
10/01
$34
10/02
$40
10/03
$43
10/04
$32
10/05
$49
busbud logoThe cheapest trip from Prague to Frankfurt am Main was searched and found on Oct 4, 2025 with a price of $32

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Frankfurt am Main, as early as possible.

You can expect to pay from $32 to $180 for a bus ticket from Prague to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-10-04.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Prague to Frankfurt am Main but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Prague to Frankfurt am Main.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Frankfurt am Main.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Prague to Frankfurt am Main.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Prague by bus?

Bus from Frankfurt am Main to Prague

You can also go to Frankfurt am Main by train

Train from Prague to Frankfurt am Main

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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