Next departures for Philadelphia to Syracuse on November 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Peter Pan + New York Trailways
Bus
Philadelphia (Schuykill & Walnut stop)
Amtrak Station
CheapestFastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Peter Pan + New York Trailways
Bus
Philadelphia (Schuykill & Walnut stop)
Syracuse (Hancock Airport)
No tags
Next departures for Philadelphia to Syracuse on November 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
CheapestFastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Next departures for Philadelphia to Syracuse on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
Cheapest
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
Fastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Next departures for Philadelphia to Syracuse on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
CheapestFastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Next departures for Philadelphia to Syracuse on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Peter Pan + New York Trailways
Bus
Philadelphia (Schuykill & Walnut stop)
Amtrak Station
CheapestFastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Peter Pan + New York Trailways
Bus
Philadelphia (Schuykill & Walnut stop)
Syracuse (Hancock Airport)
No tags
Next departures for Philadelphia to Syracuse on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
CheapestFastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Next departures for Philadelphia to Syracuse on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
Cheapest
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
Fastest
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)
No tags
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)
No tags
Last refresh of the prices: Today at 10:00 PM EST.
Compare 2 ways to go from Philadelphia to Syracuse
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 8 hours 40 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 6325 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the wifi. Peter Pan ticket prices on this trip start at $67
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
D - Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E - New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F - Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Frequently asked questions about traveling from Philadelphia, PA to Syracuse, US by bus
What is the travel distance from Philadelphia to Syracuse?
The distance separating Philadelphia and Syracuse is 220 miles (355 km).
What are the departure and arrival stations when taking the bus from Philadelphia to Syracuse?
The majority of buses traveling from Philadelphia to Syracuse start their journey at Philadelphia Airport and wind up at Regional Transportation Center. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Syracuse?
Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are NBT Bank Stadium, Onondaga Historical Association Museum, The Great New York State Fair, The Fun Warehouse and Carrier Dome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/12
$98
11/13
$77
Today
$96
11/15
$89
11/16
$97
11/17
$61
11/18
$57
11/19
$57
The cheapest trip from Philadelphia, PA to Syracuse, US was searched and found on Nov 18, 2025 with a price of $57
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Syracuse, US, as early as possible.
You can expect to pay from $57 to $154 for a bus ticket from Philadelphia, PA to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2025-11-18.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Philadelphia, PA to Syracuse, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from Philadelphia, PA to Syracuse, US was searched and found on Nov 18, 2025 with a price of $57
The bus is the cheapest travel choice for this destination
