Next departures for Philadelphia to Buffalo on November 15
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
Cheapest
Bus
Philadelphia, 199 Spring Garden St
Buffalo (BUF) Airport
Fastest
Next departures for Philadelphia to Buffalo on November 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
12 Schuylkill Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
CheapestFastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Bus
12 Schuylkill Ave
SUNY
No tags
Next departures for Philadelphia to Buffalo on November 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Buffalo (BUF) Airport
CheapestFastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Peter Pan + New York Trailways
Bus
Philadelphia (Schuykill & Walnut stop)
Ellicott St & MTC
No tags
Next departures for Philadelphia to Buffalo on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Buffalo (BUF) Airport
CheapestFastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Next departures for Philadelphia to Buffalo on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Buffalo (BUF) Airport
CheapestFastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Peter Pan + New York Trailways
Bus
Philadelphia (Schuykill & Walnut stop)
Ellicott St & MTC
No tags
Next departures for Philadelphia to Buffalo on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
Cheapest
Bus
12 Schuylkill Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
Fastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Next departures for Philadelphia to Buffalo on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Schuylkill & Walnut
Niagara Frontier Transportation Authority
Cheapest
Bus
12 Schuylkill Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
Fastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Next departures for Philadelphia to Buffalo on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
Cheapest
Bus
12 Schuylkill Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
Fastest
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Niagara Frontier Transportation Authority
No tags
Bus
Philadelphia, 199 Spring Garden St
Niagara Frontier Transportation Authority
No tags
Last refresh of the prices: Yesterday at 9:40 PM EST.
Compare 2 ways to go from Philadelphia to Buffalo
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 12 hours 25 minutes and with fares starting at just $45, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
With about 2 daily trips between Philadelphia and Buffalo, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
A good way to travel this route is with Fullington buses. The company offers 1 daily departures, with ticket prices starting at $143 and the shortest trip taking about 1365. Fullington gets you where you want to go for a fair price.
Based on 6325 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the wifi. Peter Pan ticket prices on this trip start at $103
Frequently asked questions about traveling from Philadelphia, PA to Buffalo, NY by bus
What is the travel distance from Philadelphia to Buffalo?
About 280 miles (451 km) separate Philadelphia and Buffalo.
What are the departure and arrival stations when taking the bus from Philadelphia to Buffalo?
The majority of buses traveling from Philadelphia to Buffalo start their journey at Philadelphia Airport and wind up at Buffalo Airport. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/13
$101
11/14
$121
Today
$99
11/16
$105
11/17
$78
11/18
$68
11/19
$67
11/20
$81
The cheapest trip from Philadelphia, PA to Buffalo, NY was searched and found on Nov 19, 2025 with a price of $67
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Buffalo, NY, as early as possible.
You can expect to pay from $67 to $177 for a bus ticket from Philadelphia, PA to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-11-19.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Philadelphia, PA to Buffalo, NY?
The bus is the cheapest travel choice for this destination
The cheapest trip from Philadelphia, PA to Buffalo, NY was searched and found on Nov 19, 2025 with a price of $67
The bus is the cheapest travel choice for this destination
