Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Opelika (4th Street Station) | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Opelika (4th Street Station) | Downtown Transit Center | No tags | ||||
| Bus | Opelika (4th Street Station) | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Opelika (4th Street Station) | Downtown Transit Center | No tags | ||||
| Bus | Opelika (4th Street Station) | Indianapolis Bus Station | No tags |
Get from Opelika to Indianapolis
The journey takes about 18 hours and with fares starting at just $191, it presents an excellent value for a comfortable ride.
Where are the popular stops in Opelika and Indianapolis?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Opelika to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Opelika to Indianapolis?
The cheapest bus tickets from Opelika to Indianapolis start from $191. The average price for this route is around $206. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Opelika to Indianapolis?
The average bus trip duration from Opelika to Indianapolis is 18h, covering a distance of 493 miles (795 km). The quickest bus can get you there in 16h 45m and is operated by Greyhound.
Which bus companies service the Opelika to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Opelika to Indianapolis?
The earliest bus departs from Opelika to Indianapolis at 9:00am. And the latest bus departs at 5:15pm.
What are the CO₂ emissions for the bus trip from Opelika to Indianapolis?
A bus trip from Opelika to Indianapolis generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Opelika to Indianapolis was searched and found on Mar 15, 2026 with a price of $204To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Opelika to Indianapolis, as early as possible.
