Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | St. Paul & N5th | Winona St Uni | CheapestFastest |
Last refresh of the prices: Yesterday at 9:22 PM CST.
Compare 2 ways to go from Milwaukee to Winona
Among the sustainable travel choices, the train stands out as the good way to reach Winona. The journey takes about 4 hours 18 minutes and with fares starting at just $32, it presents an excellent value for a comfortable ride.
Compare bus companies
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Frequently asked questions about traveling from Milwaukee to Winona, MN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milwaukee to Winona?
The cheapest bus tickets from Milwaukee to Winona start from $106. The average price for this route is around $106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milwaukee to Winona?
The average bus trip duration from Milwaukee to Winona is 4h 45m, covering a distance of 200 miles (321 km). The quickest bus can get you there in 4h 45m and is operated by Jefferson Lines.
Which bus companies service the Milwaukee to Winona route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Milwaukee to Winona?
The earliest bus departs from Milwaukee to Winona at 9:00am. And the latest bus departs at 9:00am.
What are the CO₂ emissions for the bus trip from Milwaukee to Winona?
A bus trip from Milwaukee to Winona generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milwaukee to Winona, MN was searched and found on Dec 3, 2025 with a price of $103To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to Winona, MN, as early as possible.
You can expect to pay from $103 to $103 for a bus ticket from Milwaukee to Winona, MN based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-12-06.
