Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tufesa | Guaymas | Cheapest | ||||
| Bus | Tufesa | Guaymas | Fastest | ||||
| Bus | Tufesa | Guaymas | No tags | ||||
| Bus | Mexicali Bus Station | Guaymas | No tags | ||||
| Bus | Mexicali Bus Station | Guaymas | No tags |
Last refresh of the prices: Yesterday at 2:29 PM PST.
Compare 2 ways to go from Mexicali to Guaymas
Among the sustainable travel choices, the bus stands out as the good way to reach Guaymas. The journey takes about 11 hours 10 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$73 - $94 | Average Duration11h 10m | 17kg CO₂e | ||
Carpool | Average Price$35 - $35 | Average Duration14h 10m | 29kg CO₂e |
Where are the popular stops in Mexicali and Guaymas?
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
Stops in Guaymas
- A
Terminal TAP de Guaymas
Calzada Agustín García López #915, Colonia Delicias, 85440 Guaymas
Compare bus companies
Frequently asked questions about traveling from Mexicali to Guaymas by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mexicali to Guaymas?
The cheapest bus tickets from Mexicali to Guaymas start from $73. The average price for this route is around $86. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mexicali to Guaymas?
The average bus trip duration from Mexicali to Guaymas is 11h 10m, covering a distance of 421 miles (678 km). The quickest bus can get you there in 10h 40m and is operated by Tufesa.
Which bus companies service the Mexicali to Guaymas route?
Several major bus companies operate on this route with 8 buses available per day, including services from Tufesa, Aguacaliente, Elite, Aguacaliente, ELITE SELECT.
What is the earliest and latest departure time for the bus from Mexicali to Guaymas?
The earliest bus departs from Mexicali to Guaymas at 12:53am. And the latest bus departs at 11:00pm.
What are the CO₂ emissions for the bus trip from Mexicali to Guaymas?
A bus trip from Mexicali to Guaymas generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mexicali to Guaymas?
According to Busbud customers, the highest-rated bus company on this route is Aguacaliente, with an average rating of 3.7 out of 5 stars based on 32 reviews.
Which bus company has the best Wi-Fi from Mexicali to Guaymas?
Based on reviews on Busbud, the bus company ELITE SELECT has the best Wi-Fi rating with a score of 3.4.
Which bus company has the most timely service from Mexicali to Guaymas?
According to Busbud traveller reviews, the most timely bus company on this route is Tufesa, with a punctuality rating of 2.7 out of 5 stars.
Which bus company has the cleanest buses from Mexicali to Guaymas?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ELITE SELECT, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexicali to Guaymas was searched and found on Dec 1, 2025 with a price of $76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Guaymas, as early as possible.
You can expect to pay from $76 to $84 for a bus ticket from Mexicali to Guaymas based on the last 2 days. You can expect to find the cheapest price for the trip at $76 which is on 2025-12-01.
