Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + Greyhound Lines Mexico + FlixBus | Bus | Mesa Bus Stop | Downtown Gray & Smith | Cheapest | ||||
 | Bus | Mesa Bus Stop | Houston Bus Station | Fastest | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Mesa Bus Stop | Houston Bus Station | No tags | ||||
| Bus | Mesa Bus Stop | Houston Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Mesa Bus Stop | Downtown Gray & Smith | No tags |
Last refresh of the prices: Today at 6:50 AM MST.
Get from Mesa to Houston
The journey takes about 1 day, 6 hours 50 minutes and with fares starting at just $224, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mesa and Houston?
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Mesa to Houston, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mesa to Houston?
The cheapest bus tickets from Mesa to Houston start from $224. The average price for this route is around $252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mesa to Houston?
The average bus trip duration from Mesa to Houston is 1d 6h, covering a distance of 992 miles (1600 km). The quickest bus can get you there in 23h 40m and is operated by Greyhound.
Which bus companies service the Mesa to Houston route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Mesa to Houston?
The earliest bus departs from Mesa to Houston at 3:50am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Mesa to Houston?
A bus trip from Mesa to Houston generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to Houston, US was searched and found on Jan 26, 2026 with a price of $234To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to Houston, US, as early as possible.
You can expect to pay from $234 to $276 for a bus ticket from Mesa to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $243 which is on 2026-01-29.
