Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | ZOB | Lyon - Perrache Bus Station | Cheapest | ||||
| Bus | ZOB | Lyon - Perrache Bus Station | Fastest | ||||
| Bus | ZOB | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Yesterday at 1:47 PM CET.
Compare 3 ways to go from Mannheim to Lyon
Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 6 hours 20 minutes and with fares starting at just $67, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$34 - $108 | Average Duration13h 35m | 12kg CO₂e | ||
Train | Average Price$52 - $246 | Average Duration5h 18m | 12kg CO₂e | |
Carpool | Average Price$67 - $74 | Average Duration6h 20m | 21kg CO₂e |
Where are the popular stops in Mannheim and Lyon?
Stops in Mannheim
- AHeinrich-von-Stephan-Straße 4-6, 68161 Mannheim, Germany
- BWilly-Brandt-Platz 17, 68161 Mannheim, Germany
- C
Uhlandstraße 7
Uhlandstraße 7, 68167 Mannheim, Germany
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Frequently asked questions about traveling from Mannheim to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mannheim to Lyon?
The cheapest bus tickets from Mannheim to Lyon start from $34. The average price for this route is around $53. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mannheim to Lyon?
The average bus trip duration from Mannheim to Lyon is 13h 35m, covering a distance of 308 miles (497 km). The quickest bus can get you there in 9h and is operated by BlaBlaCar Bus.
Which bus companies service the Mannheim to Lyon route?
Several major bus companies operate on this route with 1 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Mannheim to Lyon?
The earliest bus departs from Mannheim to Lyon at 12:15am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Mannheim to Lyon?
A bus trip from Mannheim to Lyon generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mannheim to Lyon?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.
Which bus company has the best Wi-Fi from Mannheim to Lyon?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Mannheim to Lyon?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Mannheim to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Lyon was searched and found on Dec 4, 2025 with a price of $32To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Lyon, as early as possible.
You can expect to pay from $32 to $58 for a bus ticket from Mannheim to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-12-04.
What's the cheapest way to go from Mannheim to Lyon?
The bus is the cheapest travel choice for this destination
