Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Manitowoc | San Diego (Old Town-FlixBus) | Cheapest | ||||
 | Bus | Manitowoc | Greyhound Bus Stop | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Manitowoc | UCSD Health La Jolla Station | No tags |
Last refresh of the prices: Last Thursday at 10:44 PM CST.
Get from Manitowoc to San Diego
The journey takes about 2 days, 20 hours and with fares starting at just $227, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Manitowoc to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Manitowoc to San Diego?
The cheapest bus tickets from Manitowoc to San Diego start from $227. The average price for this route is around $228. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Manitowoc to San Diego?
The average bus trip duration from Manitowoc to San Diego is 2d 20h, covering a distance of 1758 miles (2835 km). The quickest bus can get you there in 2d 20h and is operated by Greyhound.
Which bus companies service the Manitowoc to San Diego route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Manitowoc to San Diego?
The earliest bus departs from Manitowoc to San Diego at 5:45pm. And the latest bus departs at 5:45pm.
What are the CO₂ emissions for the bus trip from Manitowoc to San Diego?
A bus trip from Manitowoc to San Diego generates an estimated 71 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Manitowoc to San Diego, CA, US was searched and found on Jan 19, 2026 with a price of $220To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Manitowoc to San Diego, CA, US, as early as possible.
You can expect to pay from $220 to $235 for a bus ticket from Manitowoc to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $220 which is on 2026-01-19.
Top traveled bus routes
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