Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | University of Wisconsin - Gordon Center | Sioux Falls | No tags | ||||
| Bus | University of Wisconsin - Gordon Center | Sioux Falls | No tags |
Get from Madison to Sioux Falls
The journey takes about 23 hours 25 minutes and with fares starting at just $184, it presents an excellent value for a comfortable ride.
Where are the popular stops in Madison and Sioux Falls?
Stops in Madison
- A
UW Memorial Union
800 Langdon Street, Madison, WI 53715, USA - B
Dutch Mill Park & Ride
4 Collins Ct, Madison, WI 53716, USA
Stops in Sioux Falls
- A
Jefferson Lines Station I-29 & Maple St
4101 W Maple St, Sioux Falls, SD 57107, USA
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Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Frequently asked questions about traveling from Madison, WI to Sioux Falls by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Madison to Sioux Falls?
The cheapest bus tickets from Madison to Sioux Falls start from $184. The average price for this route is around $184. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Madison to Sioux Falls?
The average bus trip duration from Madison to Sioux Falls is 23h 25m, covering a distance of 372 miles (600 km). The quickest bus can get you there in 23h 25m and is operated by Jefferson Lines.
Which bus companies service the Madison to Sioux Falls route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Madison to Sioux Falls?
The earliest bus departs from Madison to Sioux Falls at 10:20am. And the latest bus departs at 10:20am.
What are the CO₂ emissions for the bus trip from Madison to Sioux Falls?
A bus trip from Madison to Sioux Falls generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madison, WI to Sioux Falls was searched and found on Feb 28, 2026 with a price of $179To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madison, WI to Sioux Falls, as early as possible.
You can expect to pay from $179 to $179 for a bus ticket from Madison, WI to Sioux Falls based on the last 2 days. You can expect to find the cheapest price for the trip at $179 which is on 2026-02-28.
