Bus Tickets from Lafayette, LA to San Antonio, US

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Next departures

Next departures for Lafayette to San Antonio on September 17
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + Greyhound Lines Mexico
Lafayette Transit System
San Antonio Bus StationCheapestFastest
Greyhound Lines, Inc.
Lafayette Transit System
San Antonio Bus StationNo tags
FlixBus + Valley Transit
TA Travel Center - Lafayette
San Antonio Bus StationNo tags
Greyhound Lines, Inc.
Lafayette Transit System
San Antonio Bus StationNo tags

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Compare 2 ways to go from Lafayette to San Antonio.

Bus
Average Price$54 - $139Average Duration10h 20m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$64 - $110Average Duration11h 41m
57kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Lafayette to San Antonio

Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 10 hours 20 minutes and with fares starting at just $54, it presents an excellent value for a comfortable ride.

7bus per day
10h 20mAverage Duration
$54Cheapest ticket
16kgCO₂ emissions

Bus Lafayette, LA to San Antonio, US: Trip Overview

Average ticket price$67
Average bus trip duration10h 20m
Number of daily buses7
Earliest bus departure1:30am
Distance390 miles (629 km)
Latest bus departure10:10pm

Lafayette to San Antonio Bus

With Busbud, comparing and booking tickets for a bus from Lafayette to San Antonio is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Lafayette to San Antonio.

Whether it is cheap bus tickets or more luxurious buses going to San Antonio from Lafayette, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Lafayette, LA - San Antonio, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/12
$59
09/13
$48
Today
$51
09/15
$48
09/16
No data
09/17
$68
09/18
No data
09/19
$47
busbud logoThe cheapest trip from Lafayette, LA to San Antonio, US was searched and found on Sep 19, 2025 with a price of $47

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to San Antonio, US, as early as possible.

You can expect to pay from $47 to $166 for a bus ticket from Lafayette, LA to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-09-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Lafayette to San Antonio.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Lafayette to San Antonio.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Lafayette to San Antonio.

Make a music playlist for your bus ride from Lafayette to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Lafayette, LA by bus?

Bus from San Antonio, US to Lafayette, LA

You can also go to San Antonio, US by train

Train from Lafayette, LA to San Antonio, US

Why choose Busbud?

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