Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Columbia Wabash Station | Cheapest | ||||
 | Bus | Detroit Bus Station | Columbia Wabash Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Midway Truck Plaza Bus Stop | No tags | ||||
| Bus | Detroit Bus Station | Midway Truck Plaza Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Midway Truck Plaza Bus Stop | No tags |
Last refresh of the prices: Yesterday at 7:23 PM EST.
Get from Detroit to Columbia
The journey takes about 19 hours 45 minutes and with fares starting at just $311, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Columbia?
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Detroit, MI to Columbia, MO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Columbia?
The cheapest bus tickets from Detroit to Columbia start from $311. The average price for this route is around $314. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to Columbia?
The average bus trip duration from Detroit to Columbia is 19h 45m, covering a distance of 542 miles (874 km). The quickest bus can get you there in 20h 30m and is operated by Greyhound.
Which bus companies service the Detroit to Columbia route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Detroit to Columbia?
The earliest bus departs from Detroit to Columbia at 4:20pm. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Detroit to Columbia?
A bus trip from Detroit to Columbia generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Columbia, MO was searched and found on Feb 8, 2026 with a price of $188To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Columbia, MO, as early as possible.
