How much is the bus ticket from Denver to Indianapolis?

The cheapest bus tickets from Denver to Indianapolis start from $121. The average price for this route is around $169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Denver to Indianapolis?

The average bus trip duration from Denver to Indianapolis is 1d 7h, covering a distance of 998 miles (1609 km). The quickest bus can get you there in 21h 25m and is operated by Burlington Trailways .

Which bus companies service the Denver to Indianapolis route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , Burlington Trailways .

What is the earliest and latest departure time for the bus from Denver to Indianapolis?

The earliest bus departs from Denver to Indianapolis at 7:00pm. And the latest bus departs at 8:10pm.

What are the CO₂ emissions for the bus trip from Denver to Indianapolis?

A bus trip from Denver to Indianapolis generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Denver to Indianapolis?

According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways , with an average rating of 4.2 out of 5 stars based on 20 reviews.

Which bus company has the best Wi-Fi from Denver to Indianapolis?

Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

Which bus company has the most timely service from Denver to Indianapolis?

According to Busbud traveller reviews, the most timely bus company on this route is Burlington Trailways , with a punctuality rating of 5.0 out of 5 stars.

Which bus company has the cleanest buses from Denver to Indianapolis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways , with a cleanliness rating of 5.0 out of 5 stars.

Bus Denver to Indianapolis from $136 | Refundable Tickets

Next bus departures

Next departures for Denver to Indianapolis on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	Cheapest
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on December 9
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on December 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	Cheapest
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on December 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	Cheapest
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags

Last refresh of the prices: Yesterday at 6:21 AM MST.

Compare 2 ways to go from Denver to Indianapolis

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Indianapolis. The journey takes about 1 day, 2 hours 50 minutes and with fares starting at just $142, it presents an excellent value for a comfortable ride.

1train per day

1d 2hAverage Duration

997 milesDistance

146kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$121 - $460	Average Duration1d 7h	CO₂ emissions 40kg CO₂e
Train	Average Price$142 - $274	Average Duration1d 2h	CO₂ emissions 146kg CO₂e

Where are the popular stops in Denver and Indianapolis?

Stops in Denver

A
Union Station
1701 Wynkoop St, Denver, CO 80202
Visit page
B
Bus Station
1055 19th St, Denver, CO 80202

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,415 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Denver Indianapolis recent customer reviews

Other than the bus being more than 2 hours late, everything else was good. Cleanliness of stations , restrooms and drivers and staff were excellent. We could have been better informed of delay in Denver. The took our bus off the board and we had no idea what was happening.

Cathy S.

April 2, 2019

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

Wifi5

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Denver to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Denver to Indianapolis?
The cheapest bus tickets from Denver to Indianapolis start from $121. The average price for this route is around $169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Denver to Indianapolis?
The average bus trip duration from Denver to Indianapolis is 1d 7h, covering a distance of 998 miles (1609 km). The quickest bus can get you there in 21h 25m and is operated by Burlington Trailways.
Which bus companies service the Denver to Indianapolis route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, Burlington Trailways.
What is the earliest and latest departure time for the bus from Denver to Indianapolis?
The earliest bus departs from Denver to Indianapolis at 7:00pm. And the latest bus departs at 8:10pm.
What are the CO₂ emissions for the bus trip from Denver to Indianapolis?
A bus trip from Denver to Indianapolis generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Denver to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Denver to Indianapolis?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from Denver to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Denver to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/04

$232

12/05

$380

Today

$219

12/07

$157

12/08

$167

12/09

$148

12/10

$147

12/11

No data

The cheapest trip from Denver to Indianapolis was searched and found on Dec 10, 2025 with a price of $147

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Indianapolis, as early as possible.

You can expect to pay from $147 to $380 for a bus ticket from Denver to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $147 which is on 2025-12-10.