Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Columbus (E Mound St) | Gateway Station | Cheapest | ||||
| Bus | Columbus (E Mound St) | Gateway Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 100 E Rich St | Gateway Station | No tags | ||||
| Bus | Columbus (E Mound St) | Gateway Station | No tags |
Last refresh of the prices: Last Monday at 10:46 PM EST.
Get from Columbus to St. Louis
The journey takes about 11 hours 30 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbus and St. Louis?
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
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Frequently asked questions about traveling from Columbus, OH to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbus to St. Louis?
The cheapest bus tickets from Columbus to St. Louis start from $51. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbus to St. Louis?
The average bus trip duration from Columbus to St. Louis is 11h 30m, covering a distance of 396 miles (638 km). The quickest bus can get you there in 8h 20m and is operated by Greyhound.
Which bus companies service the Columbus to St. Louis route?
What is the earliest and latest departure time for the bus from Columbus to St. Louis?
The earliest bus departs from Columbus to St. Louis at 3:50am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Columbus to St. Louis?
A bus trip from Columbus to St. Louis generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Columbus to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Columbus to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Columbus to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Columbus to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbus, OH to St. Louis was searched and found on Dec 4, 2025 with a price of $43To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to St. Louis, as early as possible.
You can expect to pay from $43 to $193 for a bus ticket from Columbus, OH to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $43 which is on 2025-12-04.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
