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Bus Columbus, OH to Knoxville, TN: Trip Overview
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Columbus to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from Columbus to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Columbus to Knoxville from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Columbus, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Columbus and Knoxville?
Frequently asked questions for your trip Columbus, OH - Knoxville, TN
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Knoxville, TN, as early as possible.
You can expect to pay from $57 to $93 for a bus ticket from Columbus, OH to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $58 which is on 2025-07-31.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Columbus to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Columbus to Knoxville, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Columbus to Knoxville.
Make a music playlist for your bus ride from Columbus to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top traveled bus routes
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