How much is the bus ticket from Columbus to Knoxville?

The cheapest bus tickets from Columbus to Knoxville start from $71. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Columbus to Knoxville?

The average bus trip duration from Columbus to Knoxville is 13h 25m, covering a distance of 278 miles (448 km). The quickest bus can get you there in 9h 25m and is operated by FlixBus .

Which bus companies service the Columbus to Knoxville route?

Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Columbus to Knoxville?

The earliest bus departs from Columbus to Knoxville at 12:50am. And the latest bus departs at 9:45am.

What are the CO₂ emissions for the bus trip from Columbus to Knoxville?

A bus trip from Columbus to Knoxville generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Columbus to Knoxville?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from Columbus to Knoxville?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Columbus to Knoxville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Columbus to Knoxville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Columbus to Knoxville from $86 | Refundable Tickets

Previously seen trips

Next departures for Columbus to Knoxville on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:25am	Columbus Bus Station	18h 10m	6:35pm	Knoxville Bus Station	No tags
	Bus	10:45pm	Columbus Bus Station	20h 10m	6:55pm	Knoxville Bus Station	No tags
	Bus	5:10am	Columbus Bus Station	13h 45m	6:55pm	Knoxville Bus Station	No tags
Greyhound + FlixBus	Bus	9:25am	Columbus (Ohio State University)	9h 30m	6:55pm	Knoxville Bus Station	No tags
Greyhound + FlixBus	Bus	9:45am	100 E Rich St	9h 10m	6:55pm	Knoxville Bus Station	No tags

Get from Columbus to Knoxville

This route is served by bus only

The journey takes about 13 hours 25 minutes and with fares starting at just $71, it presents an excellent value for a comfortable ride.

2bus per day

13h 25mAverage Duration

278 milesDistance

11kgCO₂ emissions

Where are the popular stops in Columbus and Knoxville?

Stops in Columbus

A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA

Stops in Knoxville

A
100 Kirkwood St
Knoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Visit page

Compare bus companies

Greyhound

3.5/587,403 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,464 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Columbus, OH to Knoxville, TN by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Columbus to Knoxville?
The cheapest bus tickets from Columbus to Knoxville start from $71. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbus to Knoxville?
The average bus trip duration from Columbus to Knoxville is 13h 25m, covering a distance of 278 miles (448 km). The quickest bus can get you there in 9h 25m and is operated by FlixBus.
Which bus companies service the Columbus to Knoxville route?
Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Columbus to Knoxville?
The earliest bus departs from Columbus to Knoxville at 12:50am. And the latest bus departs at 9:45am.
What are the CO₂ emissions for the bus trip from Columbus to Knoxville?
A bus trip from Columbus to Knoxville generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Columbus to Knoxville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Columbus to Knoxville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Columbus to Knoxville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Columbus to Knoxville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/25

$120

11/26

$125

Today

No data

11/28

No data

11/29

No data

11/30

$86

12/01

No data

12/02

No data

The cheapest trip from Columbus, OH to Knoxville, TN was searched and found on Nov 30, 2025 with a price of $86

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Knoxville, TN, as early as possible.

You can expect to pay from $86 to $139 for a bus ticket from Columbus, OH to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2025-11-30.