Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Charlotte Bus Station | Gateway Station | CheapestFastest | ||||
| Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Charlotte (Freedom Dr) | Gateway Station | No tags |
Last refresh of the prices: Today at 2:16 AM EST.
Get from Charlotte to St. Louis
The journey takes about 23 hours 5 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charlotte and St. Louis?
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
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Frequently asked questions about traveling from Charlotte, NC to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charlotte to St. Louis?
The cheapest bus tickets from Charlotte to St. Louis start from $91. The average price for this route is around $159. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charlotte to St. Louis?
The average bus trip duration from Charlotte to St. Louis is 23h 5m, covering a distance of 566 miles (913 km). The quickest bus can get you there in 16h 30m and is operated by FlixBus.
Which bus companies service the Charlotte to St. Louis route?
What is the earliest and latest departure time for the bus from Charlotte to St. Louis?
The earliest bus departs from Charlotte to St. Louis at 12:55am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Charlotte to St. Louis?
A bus trip from Charlotte to St. Louis generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Charlotte to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Charlotte to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Charlotte to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charlotte to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charlotte, NC to St. Louis was searched and found on Dec 8, 2025 with a price of $109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to St. Louis, as early as possible.
You can expect to pay from $109 to $223 for a bus ticket from Charlotte, NC to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $114 which is on 2025-12-15.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
