Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
BlaBlaCar Bus + BlaBlaCar Bus - Alsa | Bus | Brussels-South (Gare du Midi) | Estación Sur | Cheapest | ||||
BlaBlaCar Bus + BlaBlaCar Bus - Alsa | Bus | Brussels-South (Gare du Midi) | Aeropuerto Madrid - Barajas T4 (E) | Fastest | ||||
 | Bus | Brussels-South (Gare du Midi) | Estación Sur | No tags | ||||
 | Bus | Brussels Airport | Madrid (South) | No tags | ||||
| Bus | Brussels North Train Station | Estación Sur | No tags |
Last refresh of the prices: Today at 12:59 AM CET.
Compare 2 ways to go from Brussels to Madrid
Among the sustainable travel choices, the Carpool stands out as a good way to reach Madrid. The journey takes about 16 hours 40 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$45 - $316 | Average Duration22h 15m | 33kg CO₂e | ||
Carpool | Average Price$77 - $173 | Average Duration16h 40m | 55kg CO₂e |
Where are the popular stops in Brussels and Madrid?
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - DPachecolaan 5, 1000 Brussel, Belgium
Stops in Madrid
- AMendez Alvaro, 83, , Madrid, 28045, Spain
- CAvenida de América, 9, 28002 Madrid, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - FMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
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Frequently asked questions about traveling from Brussels to Madrid by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brussels to Madrid?
The cheapest bus tickets from Brussels to Madrid start from $45. The average price for this route is around $91. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Madrid?
The average bus trip duration from Brussels to Madrid is 22h 15m, covering a distance of 808 miles (1303 km). The quickest bus can get you there in 19h 50m and is operated by BlaBlaCar Bus.
Which bus companies service the Brussels to Madrid route?
Several major bus companies operate on this route with 15 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Brussels to Madrid?
The earliest bus departs from Brussels to Madrid at 12:45am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Brussels to Madrid?
A bus trip from Brussels to Madrid generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brussels to Madrid?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11405 reviews.
Which bus company has the best Wi-Fi from Brussels to Madrid?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Brussels to Madrid?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Madrid?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Madrid was searched and found on Feb 25, 2026 with a price of $65To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Madrid, as early as possible.
You can expect to pay from $65 to $242 for a bus ticket from Brussels to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $65 which is on 2026-02-25.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Brussels to Madrid?
The Bus is the cheapest travel choice for this destination
