How much is the bus ticket from Brussels to Lyon?

The cheapest bus tickets from Brussels to Lyon start from $27. The average price for this route is around $54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Brussels to Lyon?

The average bus trip duration from Brussels to Lyon is 11h 25m, covering a distance of 352 miles (567 km). The quickest bus can get you there in 9h 5m and is operated by BlaBlaCar Bus .

Which bus companies service the Brussels to Lyon route?

Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus , BlaBlaCar Bus .

What is the earliest and latest departure time for the bus from Brussels to Lyon?

The earliest bus departs from Brussels to Lyon at 12:15am. And the latest bus departs at 10:55pm.

What are the CO₂ emissions for the bus trip from Brussels to Lyon?

A bus trip from Brussels to Lyon generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Brussels to Lyon?

According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus , with an average rating of 3.7 out of 5 stars based on 11143 reviews.

Which bus company has the best Wi-Fi from Brussels to Lyon?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Brussels to Lyon?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Brussels to Lyon?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus , with a cleanliness rating of 4.3 out of 5 stars.

Bus Brussels to Lyon from $27 | Refundable Tickets

Next bus departures

Next departures for Brussels to Lyon on December 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:30pm	Brussels-South (Gare du Midi)	10h 45m	12:15am	Lyon - Perrache Bus Station	Cheapest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	Fastest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 15m	5:20am	Lyon - Perrache Bus Station	No tags
Bus	8:20am	Brussels Airport	15h	11:20pm	Perrache	No tags
Bus	9:45am	Brussels Airport	16h 10m	1:55am	Perrache	No tags

Next departures for Brussels to Lyon on December 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	CheapestFastest

Next departures for Brussels to Lyon on December 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	CheapestFastest

Next departures for Brussels to Lyon on December 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:40am	Brussels-South (Gare du Midi)	12h 5m	6:45pm	Lyon - Perrache Bus Station	Cheapest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	Fastest
Bus	1:30pm	Brussels-South (Gare du Midi)	10h 45m	12:15am	Lyon - Perrache Bus Station	No tags
Bus	5:55pm	Brussels-South (Gare du Midi)	10h 35m	4:30am	Lyon - Perrache Bus Station	No tags
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 15m	5:20am	Lyon - Perrache Bus Station	No tags

Next departures for Brussels to Lyon on December 5
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:30pm	Brussels-South (Gare du Midi)	10h 45m	12:15am	Lyon - Perrache Bus Station	Cheapest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	Fastest
Bus	3:11am	Brussels-South (Gare du Midi)	11h 24m	2:35pm	Lyon - Perrache Bus Station	No tags
Bus	1:15am	Brussels Airport	13h 30m	2:45pm	Perrache	No tags
Bus	7:20am	Brussels-South (Gare du Midi)	11h 25m	6:45pm	Lyon - Perrache Bus Station	No tags

Next departures for Brussels to Lyon on December 6
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:30pm	Brussels-South (Gare du Midi)	10h 45m	12:15am	Lyon - Perrache Bus Station	Cheapest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	Fastest
Bus	3:11am	Brussels-South (Gare du Midi)	11h 24m	2:35pm	Lyon - Perrache Bus Station	No tags
Bus	7:20am	Brussels-South (Gare du Midi)	11h 25m	6:45pm	Lyon - Perrache Bus Station	No tags
Bus	5:55pm	Brussels-South (Gare du Midi)	10h 35m	4:30am	Lyon - Perrache Bus Station	No tags

Next departures for Brussels to Lyon on December 7
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:20am	Brussels-South (Gare du Midi)	11h 25m	6:45pm	Lyon - Perrache Bus Station	Cheapest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	Fastest
Bus	3:11am	Brussels-South (Gare du Midi)	11h 24m	2:35pm	Lyon - Perrache Bus Station	No tags
Bus	1:30pm	Brussels-South (Gare du Midi)	10h 45m	12:15am	Lyon - Perrache Bus Station	No tags
Bus	5:55pm	Brussels-South (Gare du Midi)	10h 35m	4:30am	Lyon - Perrache Bus Station	No tags

Next departures for Brussels to Lyon on December 8
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:30pm	Brussels-South (Gare du Midi)	10h 45m	12:15am	Lyon - Perrache Bus Station	Cheapest
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 10m	5:15am	Lyon - Perrache Bus Station	Fastest
Bus	3:11am	Brussels-South (Gare du Midi)	11h 24m	2:35pm	Lyon - Perrache Bus Station	No tags
Bus	7:20am	Brussels-South (Gare du Midi)	11h 25m	6:45pm	Lyon - Perrache Bus Station	No tags
Bus	7:05pm	Brussels-South (Gare du Midi)	10h 15m	5:20am	Lyon - Perrache Bus Station	No tags

Last refresh of the prices: Today at 7:38 AM CET.

Compare 3 ways to go from Brussels to Lyon

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 7 hours 50 minutes and with fares starting at just $55, it presents an excellent value for a comfortable ride.

2carpool per day

7h 50mAverage Duration

353 milesDistance

24kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$27 - $172	Average Duration11h 25m	CO₂ emissions 14kg CO₂e
Train	Average Price$82 - $362	Average Duration4h 13m	CO₂ emissions 14kg CO₂e
Carpool	Average Price$55 - $97	Average Duration7h 50m	CO₂ emissions 24kg CO₂e

Where are the popular stops in Brussels and Lyon?

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium

Stops in Lyon

A
Lyon Airport
Visit page
B
Perrache
Rue de Esplanade, 69002 Lyon, France
Visit page
C
Lyon
8 Rue de la Paix, 69700 Givors, France
D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France
E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France
F
Les Charrières
Les Charrières, 69570 Dardilly, France
Visit page

Compare bus companies

FlixBus

3.5/511,486 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

BlaBlaCar Bus

3.5/511,182 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.6

FR bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Brussels to Lyon by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Brussels to Lyon?
The cheapest bus tickets from Brussels to Lyon start from $27. The average price for this route is around $54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Lyon?
The average bus trip duration from Brussels to Lyon is 11h 25m, covering a distance of 352 miles (567 km). The quickest bus can get you there in 9h 5m and is operated by BlaBlaCar Bus.
Which bus companies service the Brussels to Lyon route?
Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Brussels to Lyon?
The earliest bus departs from Brussels to Lyon at 12:15am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Brussels to Lyon?
A bus trip from Brussels to Lyon generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brussels to Lyon?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.
Which bus company has the best Wi-Fi from Brussels to Lyon?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Brussels to Lyon?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/29

$45

11/30

$58

Today

$39

12/02

$36

12/03

$53

12/04

$29

12/05

$39

12/06

$27

The cheapest trip from Brussels to Lyon was searched and found on Dec 6, 2025 with a price of $27

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Lyon, as early as possible.

You can expect to pay from $27 to $97 for a bus ticket from Brussels to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $27 which is on 2025-12-06.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Brussels to Lyon?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time11h 25m	Avg Price$54	Daily Departures19
Vehicle TypeTrain	Travel Time4h 13m	Avg Price$215	Daily Departures18
Vehicle TypeCarpool	Travel Time7h 50m	Avg Price$75	Daily Departures2