Bus Tickets from South Station to Chicago

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TodayMay 14
from $235
TomorrowMay 15
from $141
FriMay 16
SatMay 17
from $194
SunMay 18
from $171
MonMay 19
TueMay 20
WedMay 21

Trains leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 15 at
    Departure city: Boston
    Departure location: South Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 15 at
    Departure city: Boston
    Departure location: South Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 15 at
    Departure city: Boston
    Departure location: South Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 15 at
    Departure city: Boston
    Departure location: South Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 15 at
    Departure city: Boston
    Departure location: South Station
    Arrival time: May 16 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from South Station to Chicago.

Average Price$97 - $302Average Duration1d 6h
34kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$113 - $456Average Duration22h 22m
124kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from South Station to Chicago

Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 22 hours 22 minutes and with fares starting at just $113, it presents an excellent value for a comfortable ride.

1train per day
22h 22mAverage Duration
$113Cheapest ticket
124kgCO₂ emissions

South Station to Chicago Bus and Train

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From cheap tickets to more luxurious trip options traveling from South Station to Chicago, we offer a wide range of services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Boston - Chicago

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Popular Buses Connecting South Station

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