How much is the train ticket from Rome to Isernia?

The cheapest train tickets from Rome to Isernia start from R 295. The average price for this train route is around R 345. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.

How long is the train journey from Rome to Isernia?

The average train journey time from Rome to Isernia is 2h 15m, covering a distance of 148 km. The quickest train can get you there in 2h 5m and is operated by Trenitalia .

Which train operators serve the Rome to Isernia route?

Several major train operators run on this route, with 1 trains available per day.

What are the earliest and latest departure times for the train from Rome to Isernia?

The earliest train from Rome to Isernia departs at 09:07. And the latest train departs at 20:14.

Train Rome to Isernia from R 275

Next train departures

Next departures from Rome to Isernia on 29 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	09:07	Termini	2h 8m	11:15	Isernia	CheapestFastest

Next departures from Rome to Isernia on 30 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	09:07	Termini	2h 8m	11:15	Isernia	CheapestFastest

Next departures from Rome to Isernia on 31 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	09:07	Termini	2h 8m	11:15	Isernia	CheapestFastest
	Train	15:01	Termini	4h 1m	19:02	Isernia	No tags

Next departures from Rome to Isernia on 1 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	09:07	Termini	2h 8m	11:15	Isernia	CheapestFastest
	Train	17:40	Termini	2h 15m	19:55	Isernia	No tags

Next departures from Rome to Isernia on 2 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	09:07	Termini	2h 8m	11:15	Isernia	CheapestFastest

Next departures from Rome to Isernia on 4 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	09:07	Termini	2h 8m	11:15	Isernia	CheapestFastest

Last refresh of the prices: Last Monday at 5:12 PM CET.

Compare 3 ways to travel from Rome to Isernia

We recommend carpooling

Among the sustainable travel choices, the Carpool stands out as a good way to reach Isernia. The journey takes about 1 hour 50 minutes and with fares starting at just R 124, it presents an excellent value for a comfortable ride.

4carpool per day

1h 50mAverage duration

149 kmDistance

6kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average priceR 196 - R 1 013	Average duration6h 44m	CO₂ emissions 3kg CO₂e
Train	Average priceR 295 - R 477	Average duration2h 15m	CO₂ emissions 4kg CO₂e
Carpool	Average priceR 124 - R 362	Average duration1h 50m	CO₂ emissions 6kg CO₂e

Where are the popular train stations and stops in Rome and Isernia?

Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
Visit page
D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
Visit page
E
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Visit page
F
Fidene
Fidene, 00138 Roma RM, Italy
Visit page

Isernia

A
Isernia
Piazza della Repubblica, 9, 86170 Isernia IS, Italy
Visit page

Train Companies

Trenitalia

4/557 reviews

Staff4.6

Timeliness4.6

Cleanliness4.7

WiFi2.3

Based on 57 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the departure location but often complained about the Wi-Fi. Trenitalia ticket prices on this trip start at R 295

IT train companies: Amtrak, Trenitalia, Deutsche Bahn, Renfe, Deutsche Bahn ICE, VIA Rail Canada, RegioJet

Frequently asked questions about travelling from Rome to Isernia by train

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the train ticket from Rome to Isernia?
The cheapest train tickets from Rome to Isernia start from R 295. The average price for this train route is around R 345. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.
How long is the train journey from Rome to Isernia?
The average train journey time from Rome to Isernia is 2h 15m, covering a distance of 148 km. The quickest train can get you there in 2h 5m and is operated by Trenitalia.
Which train operators serve the Rome to Isernia route?
Several major train operators run on this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Rome to Isernia?
The earliest train from Rome to Isernia departs at 09:07. And the latest train departs at 20:14.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

26/01

R 280

27/01

R 279

Today

R 282

29/01

R 280

30/01

R 281

31/01

R 282

01/02

R 282

02/02

R 282

The cheapest trip from Rome to Isernia was searched and found on 27 Jan 2026 with a price of R 279

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Rome to Isernia as early as possible.

You can expect to pay from R 279 to R 416 for a train ticket from Rome to Isernia based on the last 2 days. You can expect to find the cheapest price for the trip at R 280, which is on 2026-01-29.