Find coaches from San Diego, CA, US to Mesa

Previously seen journeys

Next departures from San Diego to Mesa on 30 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
UCSD Health La Jolla Station
Mesa Bus StopNo tags
Greyhound + FlixBus
UCSD Health La Jolla Station
Mesa Bus StopNo tags
FlixBus + Greyhound
San Diego (Old Town-FlixBus)
Mesa Bus StopNo tags
Greyhound + FlixBus
San Diego (Old Town-FlixBus)
Mesa Bus StopNo tags
FlixBus + Greyhound
UCSD Health La Jolla Station
Mesa Bus StopNo tags

Accepted payments

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  • American Express
  • China Union Pay
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  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Get from San Diego to Mesa

busbud logoThis route is served by bus only

The journey takes about 12 hours 35 minutes, and with fares starting at just US$52, it presents an excellent value for a comfortable ride.

9bus per day
12h 35mAverage duration
505 kmDistance
13kgCO₂ emissions

Bus San Diego, CA, US to Mesa: Trip Overview

Average ticket priceUS$63
Average bus trip duration12h 35m
Number of daily buses9
Earliest bus departure07:35
Distance504 km
Latest bus departure19:35

San Diego to Mesa Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Mesa is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Mesa.

Whether it is cheap bus tickets or more luxurious buses going to Mesa from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Diego, CA, US - Mesa

  1. How much does a bus ticket from San Diego to Mesa cost?

    The bus ticket price from San Diego to Mesa starts at US$52. The best way to find cheap bus tickets from San Diego to Mesa is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from San Diego to Mesa?

    The average travel time between San Diego and Mesa is around 12h 35m, although the fastest bus will take about 8h 10m. This is the time it takes to travel the 502 km that separates the two cities.

  3. How many daily bus connections are there between San Diego and Mesa?

    The number of buses from San Diego to Mesa can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Diego to Mesa by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from San Diego to Mesa?

    When taking the bus from San Diego to Mesa, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from San Diego to Mesa?

    Buses travelling between San Diego and Mesa leave from Mission Valley Sheraton or Old Town Courtyard Marriot and arrive at Mesa Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
No data
29/10
No data
Today
No data
31/10
US$47
01/11
No data
02/11
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03/11
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04/11
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busbud logoThe cheapest trip from San Diego, CA, US to Mesa was searched and found on 31 Oct 2025 with a price of US$47

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Mesa as early as possible.

You can expect to pay from US$47 to US$47 for a bus ticket from San Diego, CA, US to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at US$47, which is on 2025-10-31.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Mesa.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Diego to Mesa.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Mesa.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Mesa while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to San Diego, CA, US by bus?

Bus from Mesa to San Diego, CA, US

Why choose Busbud?

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