Next departures from San Antonio to Chicago on 25 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
No tags
Next departures from San Antonio to Chicago on 26 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 27 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 28 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 29 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
No tags
Next departures from San Antonio to Chicago on 30 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
No tags
Next departures from San Antonio to Chicago on 1 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Greyhound Station
No tags
Bus
Tornado I-35
Chicago, IL
No tags
Next departures from San Antonio to Chicago on 2 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Bus
Tornado I-35
Chicago, IL
No tags
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Last refresh of the prices: Yesterday at 7:54 AM CST.
Compare 2 ways to travel from San Antonio to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 6 hours 55 minutes and with fares starting at just R 1 886, it presents an excellent value for a comfortable ride.
Based on 156 reviews, the company was rated 3.1 stars on Busbud. Travellers were especially satisfied with the value for money and the ticket access but often complained with the timeliness. Tornado Bus ticket prices on this trip start at R 4 555
Based on 87394 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 984
Greyhound San Antonio Chicago recent customer reviews
Leaving from Memphis we back tracked to Arkansas. The bus driver kept stopping and not letting anyone know what's going on. I even asked her what was going on and why we kept stopping and she ignored me. The bus broke down 2 hrs away from Chicago. We were supposed to arrive in Chicago downtown around 6am and did not arrive until after 10am. I also paid for two seats for me and my child and he had to sit on my lap because the bus was so crowded and uncomfortable.
1 out of 5 stars
Ashley F.
The Bus was very hot the driver kepts stopping to go to the bathroom the bus broke down & finally the driver wouldnt take me to the stopping point he said that was the end of where was going. Not according to what was purchased. Had to walk rest of the way. I was not satisfied with this service at all. I am a musician performer travel all the time meet a lot of people & all my fans musician friends & relatives will be hearing about why not to book with this company. Unsatisfied Customer.
Based on 11440 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 2 266
Based on 33 reviews, the company was rated 3 stars on Busbud. Travellers were especially satisfied with the departure location and the staff but often complained with the Wi-Fi. Valley Transit ticket prices on this trip start at R 1 745
Frequently asked questions about travelling from San Antonio, US to Chicago by bus
How much does a bus ticket from San Antonio to Chicago cost?
The bus ticket price from San Antonio to Chicago starts at R 1 886. The best way to find cheap bus tickets from San Antonio to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from San Antonio to Chicago?
The average travel time between San Antonio and Chicago is around 1d 6h, although the fastest bus will take about 22h 25m. This is the time it takes to travel the 1693 km that separates the two cities.
How many daily bus connections are there between San Antonio and Chicago?
The number of buses from San Antonio to Chicago can differ depending on the day of the week. On average, there are 34 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Antonio to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from San Antonio to Chicago?
When taking the bus from San Antonio to Chicago, you can travel comfortably and safely with Tornado Bus, Greyhound, FlixBus.
What are the departure and arrival stations when taking the bus from San Antonio to Chicago?
Buses travelling between San Antonio and Chicago leave from Tornado I-35 or San Antonio Bus Station and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
23/11
R 4 687
24/11
R 4 687
Today
R 4 687
26/11
R 4 687
27/11
R 3 714
28/11
R 4 687
29/11
R 4 687
30/11
R 4 687
The cheapest trip from San Antonio, US to Chicago was searched and found on 27 Nov 2025 with a price of R 3 714
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Chicago as early as possible.
You can expect to pay from R 3 714 to R 7 392 for a bus ticket from San Antonio, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 714, which is on 2025-11-27.
Usually Tornado Bus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from San Antonio, US to Chicago was searched and found on 27 Nov 2025 with a price of R 3 714
