Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Messina Centrale | Terminal Bus Palermo | Cheapest | ||||
 | Bus | Messina Viale Boccetta | Palermo Via Oreto | Fastest | ||||
| Bus | Piazza della Repubblica | Terminal Bus Palermo | No tags | ||||
| Bus | Messina Centrale | Terminal Bus Palermo | No tags | ||||
| Bus | Piazza della Repubblica | Terminal Bus Palermo | No tags |
Last refresh of the prices: Today at 9:26 PM CET.
Compare 4 ways to travel from Messina to Palermo
Among the sustainable travel choices, the Bus stands out as a good way to reach Palermo. The journey takes about 2 hours 45 minutes and with fares starting at just R 247, it presents an excellent value for a comfortable ride.
Where are the popular stops in Messina and Palermo?
Stops in Messina
- A
Piazza della Repubblica
Via Guido delle Colonne, 49, 98122 Messina ME, Italy - BPiazza Stazione, 98122 Messina ME, Italy
- C
Via Giuseppe Garibaldi 263
Via Giuseppe Garibaldi 263, 98122 Messina ME, Italy - D
Porto
Capitaneria di Porto, Via Vittorio Emanuele II, 111, 98100 Messina ME, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
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Frequently asked questions about travelling from Messina to Palermo by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Messina to Palermo?
The cheapest bus tickets from Messina to Palermo start at R 247. The average price for this route is around R 307. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Messina to Palermo?
The average bus journey time from Messina to Palermo is 2h 45m, covering a distance of 192 km. The fastest bus gets you there in 2h 35m and is operated by SAIS Autolinee.
Which bus companies service the Messina to Palermo route?
Several major bus companies operate on this route with 26 buses available per day, including services from SAIS Autolinee, FlixBus, Itabus.
What is the earliest and latest departure time for the bus from Messina to Palermo?
The earliest bus departs from Messina to Palermo at 04:40. And the latest bus departs at 18:35.
What are the CO₂ emissions for the bus trip from Messina to Palermo?
A bus trip from Messina to Palermo produces an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Messina to Palermo?
According to Busbud customers, the highest-rated bus company on this route is SAIS Autolinee, with an average rating of 4.2 out of 5 stars based on 484 reviews.
Which bus company has the best Wi-Fi from Messina to Palermo?
Based on reviews on Busbud, the bus company SAIS Autolinee has the best Wi-Fi rating with a score of 3.1.
Which bus company offers the most punctual service from Messina to Palermo?
According to Busbud traveller reviews, the most punctual bus company on this route is SAIS Autolinee, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Messina to Palermo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is SAIS Autolinee, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Messina to Palermo was searched and found on 12 Feb 2026 with a price of R 210To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Messina to Palermo as early as possible.
You can expect to pay from R 210 to R 498 for a bus ticket from Messina to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at R 210, which is on 2026-02-12.
Usually SAIS Autolinee will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Messina to Palermo?
The Bus is the cheapest travel choice for this destination
