Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Piazza della Repubblica | Terminal Bus Palermo | Cheapest | |||||
| Messina Viale Boccetta | Palermo Via Oreto | Fastest | |||||
| Piazza della Repubblica | Terminal Bus Palermo | No tags | |||||
 | Messina Centrale | Terminal Bus Palermo | No tags | |||||
| Piazza della Repubblica | Terminal Bus Palermo | No tags |
Last refresh of the prices: Today at 7:55 AM CET.
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Compare 4 ways to travel from Messina to Palermo
We recommend carpoolingAmong the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 2 hours 40 minutes and with fares starting at just US$14, it presents an excellent value for a comfortable ride.
Bus Messina to Palermo: Trip Overview
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Messina to Palermo Bus
Busbud helps you find a bus from Messina to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Messina to Palermo.
Whether it is cheap bus tickets or more luxurious buses going to Palermo from Messina, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Messina and Palermo?
Frequently asked questions on the trip Messina - Palermo
How much does a bus ticket from Messina to Palermo cost?
The bus ticket price from Messina to Palermo starts at US$16. The best way to find cheap bus tickets from Messina to Palermo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Messina to Palermo?
The average travel time between Messina and Palermo is around 2h 45m, although the fastest bus will take about 2h 35m. This is the time it takes to travel the 192 km that separates the two cities.
How many daily bus connections are there between Messina and Palermo?
The number of buses from Messina to Palermo can differ depending on the day of the week. On average, there are 27 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Messina to Palermo by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Messina to Palermo?
When taking the bus from Messina to Palermo, you can travel comfortably and safely with SAIS Autolinee, FlixBus, Itabus.
What are the departure and arrival stations when taking the bus from Messina to Palermo?
Buses travelling between Messina and Palermo leave from Piazza della Repubblica or Messina Centrale and arrive at Terminal Bus Palermo, Palermo Airport, Piazza Cairoli.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Messina to Palermo was searched and found on 04 Nov 2025 with a price of US$15To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Messina to Palermo as early as possible.
You can expect to pay from US$15 to US$50 for a bus ticket from Messina to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$15, which is on 2025-11-04.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Messina and Palermo!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Messina to Palermo.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Messina to Palermo.
Make a music playlist for your bus ride from Messina to Palermo, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Messina
Buses Leaving from Messina
- Bus from Messina to Hof
- Coach Messina - Trapani
- Bus Messina - Benevento
- Bus from Messina to Taormina
- Coach Messina - Catania
- Bus Messina - Palermo
- Bus from Messina to Rosarno
- Coach Messina - Giulianova
- Bus Messina - Campobasso
- Bus from Messina to Treviso
- Coach Messina - Cerignola
- Bus Messina - Frosinone
- Bus from Messina to Zona Industriale Dittaino
- Coach Messina - Pisa
- Bus Messina - Ascoli Piceno
Buses Going to Messina
- Bus from Foggia to Messina
- Coach Avellino - Messina
- Bus Porto - Messina
- Bus from Benevento to Messina
- Coach Trapani - Messina
- Bus Taranto - Messina
- Bus from Maglie to Messina
- Coach Letojanni - Messina
- Bus Sant'Alessio Siculo - Messina
- Bus from Sala Consilina to Messina
- Coach Villagonia - Messina
- Bus Rome - Messina
- Bus from Verona to Messina
- Coach Giardini Naxos - Messina
- Bus Molfetta - Messina
Popular Buses Connecting Palermo
Buses Leaving from Palermo
- Bus from Palermo to Frosinone
- Coach Palermo - Porto
- Bus Palermo - Modena
- Bus from Palermo to Maglie
- Coach Palermo - Catania
- Bus Palermo - Trapani
- Bus from Palermo to Padova
- Coach Palermo - Milano
- Bus Palermo - Rovereto
- Bus from Palermo to Corigliano Calabro
- Coach Palermo - Foligno
- Bus Palermo - Lauria
- Bus from Palermo to Bari
- Coach Palermo - Bologna
- Bus Palermo - Lanciano
Buses Going to Palermo
- Bus from Frosinone to Palermo
- Coach Bari - Palermo
- Bus Cosenza - Palermo
- Bus from Modena to Palermo
- Coach Outlet - Palermo
- Bus Catania - Palermo
- Bus from Zona Industriale Zappulla to Palermo
- Coach Castelvetrano - Palermo
- Bus Vibo Valentia - Palermo
- Bus from Cariati to Palermo
- Coach Ancona - Palermo
- Bus Lamezia Terme - Palermo
- Bus from Portogruaro to Palermo
- Coach Ventimiglia - Palermo
- Bus Macari - Palermo