Find coaches from Harrisburg to Chicago

Next departures

Next departures from Harrisburg to Chicago on 30 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Harrisburg Bus Station
Downtown Greyhound StationCheapestFastest
FlixBus
Harrisburg Bus Station
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
Harrisburg Bus Station
537-517 W. Jackson BlvdNo tags
Greyhound Lines, Inc. + FlixBus
Harrisburg Bus Station
Chicago 95Th & Dan RyanNo tags
Greyhound Lines, Inc.
Harrisburg Bus Station
537-517 W. Jackson BlvdNo tags

Last refresh of the prices: Yesterday at 2:26 AM EDT.

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Compare 2 ways to travel from Harrisburg to Chicago

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 18 hours 10 minutes and with fares starting at just US$63, it presents an excellent value for a comfortable ride.

8bus per day
18h 10mAverage duration
916 kmDistance
23kgCO₂ emissions
Bus
Average priceUS$63 - US$308Average duration18h 10m
23kg CO₂e
Train
Average priceUS$102 - US$828Average duration20h 36m
84kg CO₂e

Bus Harrisburg to Chicago: Trip Overview

Average ticket priceUS$108
Average bus trip duration18h 10m
Number of daily buses8
Earliest bus departure01:30
Distance916 km
Latest bus departure21:10

Harrisburg to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Harrisburg to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Harrisburg to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Harrisburg to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Harrisburg - Chicago

  1. How much does a bus ticket from Harrisburg to Chicago cost?

    The bus ticket price from Harrisburg to Chicago starts at US$63. The best way to find cheap bus tickets from Harrisburg to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Harrisburg to Chicago?

    The average travel time between Harrisburg and Chicago is around 18h 10m, although the fastest bus will take about 14h 45m. This is the time it takes to travel the 920 km that separates the two cities.

  3. How many daily bus connections are there between Harrisburg and Chicago?

    The number of buses from Harrisburg to Chicago can differ depending on the day of the week. On average, there are 8 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Harrisburg to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Harrisburg to Chicago?

    When taking the bus from Harrisburg to Chicago, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$104
29/10
US$104
Today
US$145
31/10
US$96
01/11
No data
02/11
US$66
03/11
US$60
04/11
US$63
busbud logoThe cheapest trip from Harrisburg to Chicago was searched and found on 03 Nov 2025 with a price of US$60

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Chicago as early as possible.

You can expect to pay from US$60 to US$166 for a bus ticket from Harrisburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$60, which is on 2025-11-03.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Harrisburg to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Harrisburg to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Harrisburg to Chicago that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Harrisburg to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Harrisburg to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Chicago to Harrisburg

You can also go to Chicago by train

Train from Harrisburg to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

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