Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Spartanburg | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Spartanburg | Downtown Greyhound Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Spartanburg | Downtown Greyhound Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Spartanburg | 537-517 W. Jackson Blvd | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Spartanburg | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 08:09 EST.
Compare 2 ways to travel from Spartanburg to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 20 hours 20 minutes and with fares starting at just £96, it presents an excellent value for a comfortable ride.
Where are the popular stops in Spartanburg and Chicago?
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling by bus from Spartanburg to Chicago
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Spartanburg to Chicago?
The cheapest coach tickets from Spartanburg to Chicago start from £96. The average price for this route is around £151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Spartanburg to Chicago?
The average bus journey time from Spartanburg to Chicago is 20h 20m, covering a distance of 554 miles. The fastest bus can take you there in 20h 20m and is operated by Greyhound.
Which bus companies service the Spartanburg to Chicago route?
What is the earliest and latest departure time for the bus from Spartanburg to Chicago?
The earliest bus departs from Spartanburg to Chicago at 06:20. And the latest bus departs at 19:55.
What are the CO₂ emissions for the bus trip from Spartanburg to Chicago?
A bus journey from Spartanburg to Chicago produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Spartanburg to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which company has the best Wi-Fi from Spartanburg to Chicago?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Spartanburg to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Spartanburg to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Spartanburg to Chicago was searched and found on 6 Dec 2025 with a price of £70To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Chicago as early as possible.
You can expect to pay from £70 to £202 for a bus ticket from Spartanburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £70, which is on 2025-12-06.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Spartanburg to Chicago?
The bus is the cheapest travel choice for this destination
