Find coaches from San Luis, US to Santa Ana, SON, MX

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Tomorrow10 Sept
from US$47
Thu11 Sept
Fri12 Sept
Sat13 Sept
Sun14 Sept
Mon15 Sept
Tue16 Sept
Wed17 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 10 September at
    Departure city: San Luis
    Departure location: San Luis Río Colorado
    Arrival time: 10 September at
    Destination city: Santa Ana
    Destination location: Santa Ana
    Operated by: Autobuses AguacalienteAutobuses Aguacaliente
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 10 September at
    Departure city: San Luis
    Departure location: San Luis Río Colorado
    Arrival time: 11 September at
    Destination city: Santa Ana
    Destination location: Santa Ana
    Operated by: Autobuses AguacalienteAutobuses Aguacaliente
    Vehicle: BusDuration:
  • Departure time: 10 September at
    Departure city: San Luis
    Departure location: San Luis Río Colorado
    Arrival time: 11 September at
    Destination city: Santa Ana
    Destination location: Santa Ana
    Operated by: Autobuses AguacalienteAutobuses Aguacaliente
    Vehicle: BusDuration:

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Bus San Luis, US to Santa Ana, SON, MX: Trip Overview

Average ticket priceUS$46
Average bus trip duration5h 35m
Number of daily buses4
Earliest bus departure01:25
Distance253 miles
Latest bus departure20:35

San Luis to Santa Ana Bus

With Busbud, comparing and booking tickets for a bus from San Luis to Santa Ana is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from San Luis to Santa Ana will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from San Luis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Luis, US - Santa Ana, SON, MX

  1. What's the distance between San Luis and Santa Ana by coach?

    The journey from San Luis to Santa Ana by coach covers an approximate distance of 255 miles (410 km).

  2. What is the best way to go from San Luis to Santa Ana without flying?

    To travel from San Luis to Santa Ana without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/09
No data
08/09
US$46
Today
No data
10/09
US$47
11/09
No data
12/09
No data
13/09
No data
14/09
No data
busbud logoThe cheapest trip from San Luis, US to Santa Ana, SON, MX was searched and found on 8 Sept 2025 with a price of US$46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis, US to Santa Ana, SON, MX as early as possible.

You can expect to pay from US$46 to US$47 for a bus ticket from San Luis, US to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at US$47, which is on 2025-09-10.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Luis to Santa Ana.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from San Luis to Santa Ana, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Luis to Santa Ana.

Tune out to the fine sounds of your best music playlist on your bus trip from San Luis to Santa Ana while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

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