Next departures to Santa Maria
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 21 June atDeparture city: San FranciscoDeparture location: 409 Townsend St, SFArrival time: 21 June atDestination city: Santa MariaDestination location: Nicholson AveOperated by: FlixBus
Vehicle: BusDuration: - Departure time: 21 June atDeparture city: San FranciscoDeparture location: Mission St & Fremont StArrival time: 21 June atDestination city: Santa MariaDestination location: Nicholson AveOperated by: Amtrak
Vehicle: BusDuration: - Departure time: 21 June atDeparture city: San FranciscoDeparture location: Mission St & Fremont StArrival time: 21 June atDestination city: Santa MariaDestination location: Nicholson AveOperated by: AmtrakVehicle: BusDuration:
- Departure time: 21 June atDeparture city: San FranciscoDeparture location: Mission St & Fremont StArrival time: 21 June atDestination city: Santa MariaDestination location: Nicholson AveOperated by: AmtrakVehicle: BusDuration:
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Bus San Francisco to Santa Maria: Trip Overview
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San Francisco to Santa Maria Bus
Busbud helps you find a bus from San Francisco to Santa Maria. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from San Francisco to Santa Maria from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Santa Maria from San Francisco, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions on the trip San Francisco (CA), US - Santa Maria (CA), US
What's the distance between San Francisco and Santa Maria by coach?
The journey from San Francisco to Santa Maria by coach covers an approximate distance of 225 miles (362 km).
How can I get from San Francisco to Santa Maria without driving?
You can reach Santa Maria from San Francisco by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Francisco to Santa Maria was searched and found on 21 Jun 2025 with a price of US$44To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco to Santa Maria as early as possible.
You can expect to pay from US$44 to US$97 for a bus ticket from San Francisco to Santa Maria based on the last 2 days. You can expect to find the cheapest price for the trip at US$44, which is on 2025-06-21.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and Santa Maria!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Francisco to Santa Maria, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Francisco to Santa Maria.
Tune out to the fine sounds of your best music playlist on your bus trip from San Francisco to Santa Maria while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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