Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Prague (Central Bus Station Florenc) | Hotelu Grand | Cheapest | ||||
Maksymiuk FOP | Bus | Florenc Bus Terminal | Petrol station "OMV", Brno | Fastest | ||||
Vlak společnosti Gepard Express | Bus | Vaclav Havel Airport Prague | bus station Grand | No tags | ||||
 | Bus | Florenc Bus Terminal | ÚAN Zvonařka | No tags | ||||
 | Bus | Praha [*CZ],,ÚAN Florenc, platform 6, Prague | hotel GRAND, Brno | No tags |
Last refresh of the prices: Today at 23:31 CET.
Compare 2 ways to travel from Prague to Brno
Among the sustainable travel choices, the Bus stands out as a good way to reach Brno. The journey takes about 2 hours 35 minutes and with fares starting at just £7, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Brno?
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CAviatická, 161 08, Praha 6, Czechia
- DChlumecká, 198 00 Praha 20, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Brno
- AZvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic
- BBenešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic
- CBrno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia
- DNádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia
- E
Ústřední hřbitov
Vídeňská 306/94, Štýřice, 639 00 Brno-Brno-střed, Czechia - F
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia
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Frequently asked questions about travelling by bus from Prague to Brno
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Prague to Brno?
The cheapest coach tickets from Prague to Brno start from £7. The average price for this route is around £10. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Prague to Brno?
The average bus journey time from Prague to Brno is 2h 35m, covering a distance of 116 miles. The fastest bus can take you there in 2h and is operated by Maksymiuk FOP.
Which bus companies service the Prague to Brno route?
Several major bus companies operate on this route with 64 buses available per day, including services from FlixBus, RegioJet, Avtokombinat-1 OOO, Maksymiuk FOP, IC Bus, Slovak Lines, A-Express, Musil Tour, Gepard Express, Monobus.
What is the earliest and latest departure time for the bus from Prague to Brno?
The earliest bus departs from Prague to Brno at 01:45. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Prague to Brno?
A bus journey from Prague to Brno produces an estimated 5 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Prague to Brno?
According to Busbud customers, the highest-rated bus company on this route is IC Bus, with an average rating of 4.5 out of 5 stars based on 20 reviews.
Which company has the best Wi-Fi from Prague to Brno?
Based on Busbud reviews, the bus company Slovak Lines has the best Wi-Fi rating with a score of 4.1.
Which bus company offers the most punctual service from Prague to Brno?
According to Busbud traveller reviews, the most punctual bus company on this route is IC Bus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brno?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is IC Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Brno was searched and found on 11 Feb 2026 with a price of £6To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brno as early as possible.
You can expect to pay from £6 to £23 for a bus ticket from Prague to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at £6, which is on 2026-02-14.
What's the cheapest way to go from Prague to Brno?
The Bus is the cheapest travel choice for this destination
