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Compare 2 ways to travel from Plzeň to Brussels

Bus
Average priceUS$74 - US$74Average duration10h 30m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$130 - US$168Average duration11h 33m
16kg CO₂e5 out of 5 stars
busbud logoBusbud recommends taking the bus from Plzeň to Brussels

Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 10 hours 30 minutes and with fares starting at just US$74, it presents an excellent value for a comfortable ride.

1bus per day
10h 30mAverage duration
US$74Cheapest ticket
16kgCO₂ emissions

Bus Plzeň to Brussels: Trip Overview

Average ticket priceUS$74
Average bus trip duration10h 30m
Number of daily buses1
Earliest bus departure19:30
Distance405 miles

Plzeň to Brussels Bus

With Busbud, comparing and booking tickets for a bus from Plzeň to Brussels is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Plzeň to Brussels from the most reliable bus companies operating this trip.

Discover how much the bus trip from Plzeň to Brussels will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Plzeň - Brussels

  1. What's the distance between Plzeň and Brussels by coach?

    The distance between Plzeň and Brussels by coach is approximately 405 miles (654 km).

  2. What is the best way to go from Plzeň to Brussels without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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15/08
US$72
busbud logoThe cheapest trip from Plzeň to Brussels was searched and found on 15 Aug 2025 with a price of US$72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Plzeň to Brussels as early as possible.

You can expect to pay from US$72 to US$72 for a bus ticket from Plzeň to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$72, which is on 2025-08-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Plzeň to Brussels.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Plzeň to Brussels, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Plzeň to Brussels will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Plzeň to Brussels.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Plzeň to Brussels?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Plzeň by bus?

Bus from Plzeň to Brussels

You can also go to Brussels by train

Train from Plzeň to Brussels

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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