Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | park Aurelia | Terminal Bus Palermo | Cheapest | ||||
| Bus | park Aurelia | Terminal Bus Palermo | Fastest |
Last refresh of the prices: Last Monday at 22:04 CET.
Compare 2 ways to travel from Pisa to Palermo
Among the sustainable travel choices, the Bus stands out as a good way to reach Palermo. The journey takes about 21 hours 35 minutes and with fares starting at just £26, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£26 - £37 | Average duration21h 35m | 17kg CO₂e | ||
Carpool | Average price£59 - £59 | Average duration14h 10m | 28kg CO₂e |
Where are the popular stops in Pisa and Palermo?
Stops in Pisa
- BVia Pietrasantina, 56123 Pisa PI
- C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Based on 12162 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at £26
Frequently asked questions about travelling by bus from Pisa to Palermo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Pisa to Palermo?
The cheapest coach tickets from Pisa to Palermo start from £26. The average price for this route is around £33. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Pisa to Palermo?
The average bus journey time from Pisa to Palermo is 21h 35m, covering a distance of 416 miles. The fastest bus can take you there in 21h and is operated by FlixBus.
Which bus companies service the Pisa to Palermo route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Pisa to Palermo?
The earliest bus departs from Pisa to Palermo at 12:00. And the latest bus departs at 17:25.
What are the CO₂ emissions for the bus trip from Pisa to Palermo?
A bus journey from Pisa to Palermo produces an estimated 17 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Palermo was searched and found on 2 Feb 2026 with a price of £23To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Palermo as early as possible.
You can expect to pay from £23 to £31 for a bus ticket from Pisa to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at £23, which is on 2026-02-02.
What's the cheapest way to go from Pisa to Palermo?
The Bus is the cheapest travel choice for this destination
