Find coaches from Palermo to Siena

Next departures

Next departures from Palermo to Siena on 2 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Terminal Bus Palermo
Siena Train StationCheapestFastest
Flixbus
Terminal Bus Palermo
Siena Train StationNo tags
Flixbus
Terminal Bus Palermo
Siena Train StationNo tags
Flixbus
Terminal Bus Palermo
Viale Toselli (Penny Market)No tags

Last refresh of the prices: Today at 00:14 CEST.

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Compare 2 ways to travel from Palermo to Siena

Bus
Average priceUS$58 - US$197Average duration18h 55m
15kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$87 - US$87Average duration13h 20m
25kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Palermo to Siena

Among the sustainable travel choices, the carpool stands out as a good way to reach Siena. The journey takes about 13 hours 20 minutes and with fares starting at just US$87, it presents an excellent value for a comfortable ride.

1carpool per day
13h 20mAverage duration
US$87Cheapest ticket
25kgCO₂ emissions

Bus Palermo to Siena: Trip Overview

Average ticket priceUS$123
Average bus trip duration18h 55m
Number of daily buses4
Earliest bus departure11:10
Distance376 miles
Latest bus departure18:15

Palermo to Siena Bus

Busbud helps you find a bus from Palermo to Siena. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Palermo to Siena.

Whether it is cheap bus tickets or more luxurious buses going to Siena from Palermo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Palermo - Siena

  1. How far is Siena from Palermo by coach?

    The journey from Palermo to Siena by coach covers an approximate distance of 375 miles (604 km).

  2. Is there a way to reach Siena from Palermo without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/09
No data
01/10
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Today
US$132
03/10
No data
04/10
No data
05/10
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06/10
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07/10
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busbud logoThe cheapest trip from Palermo to Siena was searched and found on 2 Oct 2025 with a price of US$132

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Siena as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Palermo and Siena!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Palermo to Siena.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Palermo to Siena.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Palermo to Siena.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Palermo by bus?

Bus from Siena to Palermo

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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