Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Palermo | Brindisi Bus Stop | CheapestFastest |
Last refresh of the prices: Last Monday at 17:51 CET.
Get from Palermo to Brindisi
The journey takes about 23 hours 35 minutes, and with fares starting at just £65, it presents an excellent value for a comfortable ride.
Where are the popular stops in Palermo and Brindisi?
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Stops in Brindisi
- AVia Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy
- C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy - D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy - E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy - F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy
Compare bus companies
Based on 11518 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £65
Frequently asked questions about travelling by bus from Palermo to Brindisi
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Palermo to Brindisi?
The cheapest coach tickets from Palermo to Brindisi start from £65. The average price for this route is around £75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Palermo to Brindisi?
The average bus journey time from Palermo to Brindisi is 23h 35m, covering a distance of 299 miles. The fastest bus can take you there in 23h 35m and is operated by FlixBus.
Which bus companies service the Palermo to Brindisi route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Palermo to Brindisi?
The earliest bus departs from Palermo to Brindisi at 17:10. And the latest bus departs at 17:10.
What are the CO₂ emissions for the bus trip from Palermo to Brindisi?
A bus journey from Palermo to Brindisi produces an estimated 12 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Brindisi was searched and found on 8 Dec 2025 with a price of £90To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Brindisi as early as possible.
You can expect to pay from £90 to £91 for a bus ticket from Palermo to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at £90, which is on 2025-12-08.
