Find coaches from La Spezia to Palermo

Find affordable coach tickets from La Spezia to Palermo with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.

Compare 2 ways to travel from La Spezia to Palermo

Bus
Average priceUS$129 - US$225Average duration22h 10m
18kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average priceUS$113 - US$113Average duration13h 10m
31kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from La Spezia to Palermo

Among the sustainable travel choices, the bus stands out as a good way to reach Palermo. The journey takes about 22 hours 10 minutes and with fares starting at just US$129, it presents an excellent value for a comfortable ride.

2bus per day
22h 10mAverage duration
US$129Cheapest ticket
18kgCO₂ emissions

Bus La Spezia to Palermo: Trip Overview

Average ticket priceUS$185
Average bus trip duration22h 10m
Number of daily buses2
Earliest bus departure07:10
Distance453 miles
Latest bus departure17:55

La Spezia to Palermo Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from La Spezia to Palermo.

We make sure you can find a bus service from La Spezia to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from La Spezia to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip La Spezia - Palermo

  1. How far is Palermo from La Spezia by coach?

    The journey from La Spezia to Palermo by coach covers an approximate distance of 453 miles (730 km).

  2. What is the best way to go from La Spezia to Palermo without flying?

    To travel from La Spezia to Palermo without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/08
No data
08/08
No data
Today
No data
10/08
No data
11/08
US$103
12/08
No data
13/08
No data
14/08
No data
busbud logoThe cheapest trip from La Spezia to Palermo was searched and found on 11 Aug 2025 with a price of US$103

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Spezia to Palermo as early as possible.

You can expect to pay from US$103 to US$117 for a bus ticket from La Spezia to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$103, which is on 2025-08-11.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from La Spezia to Palermo but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from La Spezia to Palermo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from La Spezia to Palermo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from La Spezia to Palermo while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to La Spezia by bus?

Bus from La Spezia to Palermo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting La Spezia

Buses Leaving from La Spezia

Buses Going to La Spezia

Popular Buses Connecting Palermo

Buses Leaving from Palermo

Buses Going to Palermo