Find coaches from Knoxville, TN to Durham, NC, US

Bus Knoxville, TN to Durham, NC, US: Trip Overview

Average ticket priceUS$97
Average bus trip duration13h 35m
Number of daily buses1
Earliest bus departure19:25
Distance278 miles

Knoxville to Durham Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Durham.

We make sure you can find a bus service from Knoxville to Durham from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Knoxville to Durham, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Knoxville, TN - Durham, NC, US

  1. What's the distance between Knoxville and Durham by coach?

    The distance between Knoxville and Durham by coach is approximately 281 miles (453 km).

  2. What is the best way to go from Knoxville to Durham without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/08
No data
31/08
No data
Today
US$112
02/09
No data
03/09
US$74
04/09
US$60
05/09
No data
06/09
US$70
busbud logoThe cheapest trip from Knoxville, TN to Durham, NC, US was searched and found on 4 Sept 2025 with a price of US$60

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Durham, NC, US as early as possible.

You can expect to pay from US$60 to US$112 for a bus ticket from Knoxville, TN to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$60, which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Durham, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Durham that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Knoxville, TN by bus?

Bus from Durham, NC, US to Knoxville, TN

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