Find coaches from Indianapolis to Des Moines

Tomorrow1 Aug
from US$105
Sat2 Aug
Sun3 Aug
Mon4 Aug
from US$75
Tue5 Aug
Wed6 Aug
Thu7 Aug
from US$77
Fri8 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 1 August at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 2 August at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 1 August at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: 1 August at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 2 August at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: 1 August at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: 1 August at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:

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Bus Indianapolis to Des Moines: Trip Overview

Average ticket priceUS$93
Average bus trip duration18h
Number of daily buses2
Earliest bus departure07:10
Distance410 miles
Latest bus departure21:35

Indianapolis to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.

Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - Des Moines

  1. What's the distance between Indianapolis and Des Moines by coach?

    The distance between Indianapolis and Des Moines by coach is approximately 410 miles (661 km).

  2. How can I travel from Indianapolis to Des Moines avoiding air travel?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/07
US$116
30/07
US$82
Today
US$83
01/08
US$107
02/08
No data
03/08
No data
04/08
US$83
05/08
No data
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on 30 Jul 2025 with a price of US$82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines as early as possible.

You can expect to pay from US$82 to US$178 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$83, which is on 2025-08-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Indianapolis to Des Moines will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Des Moines

Why choose Busbud?

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