Find coaches from Gainesville, FL to Tupelo

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Previously seen journeys

One passenger / one way

  • Departure time: 3 October at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: 3 October at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 3 October at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: 4 October at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 3 October at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: 4 October at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 3 October at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: 4 October at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 3 October at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: 4 October at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

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Bus Gainesville, FL to Tupelo: Trip Overview

Average ticket priceUS$110
Average bus trip duration14h 5m
Number of daily buses4
Earliest bus departure01:10
Distance485 miles
Latest bus departure22:40

Gainesville to Tupelo Bus

With Busbud, comparing and booking tickets for a bus from Gainesville to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Gainesville to Tupelo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Gainesville to Tupelo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Gainesville, FL - Tupelo

  1. How far is Tupelo from Gainesville by coach?

    The journey from Gainesville to Tupelo by coach covers an approximate distance of 488 miles (787 km).

  2. What is the best way to go from Gainesville to Tupelo without flying?

    To travel from Gainesville to Tupelo without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
27/08
No data
28/08
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Today
US$97
30/08
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31/08
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01/09
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02/09
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03/09
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busbud logoThe cheapest trip from Gainesville, FL to Tupelo was searched and found on 29 Aug 2025 with a price of US$97

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Tupelo as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Gainesville to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Tupelo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Gainesville to Tupelo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Gainesville to Tupelo.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Gainesville, FL by bus?

Bus from Tupelo to Gainesville, FL

Why choose Busbud?

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