Find coaches from Gainesville, FL to Panama City, US

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Today6 Aug
from US$45
Tomorrow7 Aug
Fri8 Aug
from US$50
Sat9 Aug
from US$49
Sun10 Aug
Mon11 Aug
from US$45
Tue12 Aug
Wed13 Aug

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 8 August at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: 8 August at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 8 August at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: 8 August at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 8 August at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: 8 August at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Gainesville, FL to Panama City, US: Trip Overview

Average ticket priceUS$52
Average bus trip duration6h 20m
Number of daily buses1
Earliest bus departure08:20
Distance210 miles
Latest bus departure15:50

Gainesville to Panama City Bus

With Busbud, comparing and booking tickets for a bus from Gainesville to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Gainesville to Panama City from the most reliable bus companies operating this trip.

Discover how much the bus trip from Gainesville to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Gainesville, FL - Panama City, US

  1. How far is Panama City from Gainesville by coach?

    The journey from Gainesville to Panama City by coach covers an approximate distance of 204 miles (328 km).

  2. Is there a way to reach Panama City from Gainesville without a car?

    You can reach Panama City from Gainesville by coach, as there are regular services between the two locations. Depending on your preferences, carpooling can also be considered as an option.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/08
US$40
05/08
No data
Today
US$37
07/08
No data
08/08
US$42
09/08
US$42
10/08
No data
11/08
US$37
busbud logoThe cheapest trip from Gainesville, FL to Panama City, US was searched and found on 6 Aug 2025 with a price of US$37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Panama City, US as early as possible.

You can expect to pay from US$37 to US$62 for a bus ticket from Gainesville, FL to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$37, which is on 2025-08-11.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Gainesville to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Panama City, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Gainesville to Panama City will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Gainesville to Panama City.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Gainesville, FL by bus?

Bus from Gainesville, FL to Panama City, US

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