Find coaches from Detroit, MI to St. Louis

Find affordable coach tickets from Detroit, MI to St. Louis with flexible options. Book your journey now

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Today7 Aug
from US$133
Tomorrow8 Aug
from US$139
Sat9 Aug
from US$110
Sun10 Aug
from US$110
Mon11 Aug
from US$100
Tue12 Aug
from US$88
Wed13 Aug
from US$88
Thu14 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 8 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 9 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 8 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 8 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 8 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 9 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Detroit to St. Louis

Bus
Average priceUS$69 - US$183Average duration15h 30m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$75 - US$221Average duration13h 41m
67kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Detroit to St. Louis

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 13 hours 41 minutes and with fares starting at just US$75, it presents an excellent value for a comfortable ride.

1train per day
13h 41mAverage duration
US$75Cheapest ticket
67kgCO₂ emissions

Bus Detroit, MI to St. Louis: Trip Overview

Average ticket priceUS$89
Average bus trip duration15h 30m
Number of daily buses4
Earliest bus departure06:40
Distance454 miles
Latest bus departure23:25

Detroit to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Detroit to St. Louis.

We make sure you can find a bus service from Detroit to St. Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Detroit, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Detroit, MI - St. Louis

  1. What's the distance between Detroit and St. Louis by coach?

    The distance between Detroit and St. Louis by coach is approximately 454 miles (733 km).

  2. What is the best way to go from Detroit to St. Louis without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/08
US$115
06/08
US$96
Today
US$168
08/08
US$150
09/08
US$103
10/08
US$126
11/08
US$95
12/08
US$81
busbud logoThe cheapest trip from Detroit, MI to St. Louis was searched and found on 12 Aug 2025 with a price of US$81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to St. Louis as early as possible.

You can expect to pay from US$81 to US$168 for a bus ticket from Detroit, MI to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$81, which is on 2025-08-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Detroit to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to St. Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Detroit to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Detroit, MI to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Detroit, MI by bus?

Bus from Detroit, MI to St. Louis

You can also go to St. Louis by train

Train from Detroit, MI to St. Louis

Why choose Busbud?

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