Find coaches from Chicago to St. Louis

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Today11 Aug
from US$136
Tomorrow12 Aug
from US$49
Wed13 Aug
from US$48
Thu14 Aug
from US$48
Fri15 Aug
from US$48
Sat16 Aug
from US$48
Sun17 Aug
from US$51
Mon18 Aug
from US$34

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 12 August at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: 12 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 12 August at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: 12 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: 12 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: 12 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: 12 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Chicago to St. Louis

Average priceUS$32 - US$182Average duration7h 55m
10kg CO₂e5 out of 5 stars
Most eco-friendly
Average priceUS$30 - US$98Average duration5h 1m
38kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from Chicago to St. Louis

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 5 hours 1 minute and with fares starting at just US$30, it presents an excellent value for a comfortable ride.

5train per day
5h 1mAverage duration
US$30Cheapest ticket
38kgCO₂ emissions

Bus Chicago to St. Louis: Trip Overview

Average ticket priceUS$50
Average bus trip duration7h 55m
Number of daily buses12
Earliest bus departure00:15
Distance253 miles
Latest bus departure23:50

Chicago to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Chicago to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Chicago to St. Louis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Chicago to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Chicago - St. Louis

  1. How far is St. Louis from Chicago by coach?

    The journey from Chicago to St. Louis by coach covers an approximate distance of 260 miles (419 km).

  2. Is there a way to reach St. Louis from Chicago without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/08
US$52
10/08
US$85
Today
US$49
12/08
US$41
13/08
US$40
14/08
US$40
15/08
US$40
16/08
US$40
busbud logoThe cheapest trip from Chicago to St. Louis was searched and found on 13 Aug 2025 with a price of US$40

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to St. Louis as early as possible.

You can expect to pay from US$40 to US$160 for a bus ticket from Chicago to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$40, which is on 2025-08-13.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Chicago to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to St. Louis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to St. Louis that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to St. Louis.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Chicago by bus?

Bus from Chicago to St. Louis

You can also go to St. Louis by train

Train from Chicago to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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