Find coaches from Chicago to Santa Ana, US

Next departures

Next departures from Chicago to Santa Ana on 19 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
537-517 W. Jackson Blvd
Anaheim Regional Transportation Intermodal CenterCheapest
FlixBus + Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Santa Ana Bus StationFastest
FlixBus + Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Anaheim Regional Transportation Intermodal CenterNo tags
Greyhound Lines, Inc.
537-517 W. Jackson Blvd
Anaheim Regional Transportation Intermodal CenterNo tags
FlixBus + Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Anaheim Regional Transportation Intermodal CenterNo tags

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Bus Chicago to Santa Ana, US: Trip Overview

Average ticket priceUS$297
Average bus trip duration2d 5h
Number of daily buses17
Earliest bus departure00:40
Distance1731 miles
Latest bus departure23:50

Chicago to Santa Ana Bus

Busbud helps you find a bus from Chicago to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Chicago to Santa Ana will be provided by the most trusted bus companies.

Discover how much the bus trip from Chicago to Santa Ana will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Chicago - Santa Ana, US

  1. What's the distance between Chicago and Santa Ana by coach?

    The distance between Chicago and Santa Ana by coach is approximately 1730 miles (2790 km).

  2. What is the best way to go from Chicago to Santa Ana without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
16/09
No data
17/09
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Today
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19/09
US$185
20/09
No data
21/09
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22/09
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23/09
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busbud logoThe cheapest trip from Chicago to Santa Ana, US was searched and found on 19 Sept 2025 with a price of US$185

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Santa Ana, US as early as possible.

You can expect to pay from US$185 to US$337 for a bus ticket from Chicago to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$185, which is on 2025-09-19.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and Santa Ana!

Much more than a mere vehicle taking you from Chicago to Santa Ana, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Chicago to Santa Ana will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to Santa Ana.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Chicago by bus?

Bus from Santa Ana, US to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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