Find coaches from Buffalo, NY to Spartanburg

Next departures

Next departures from Buffalo to Spartanburg on 2 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Niagara Frontier Transportation Authority
SpartanburgCheapest
FlixBus + Greyhound Lines, Inc.
Buffalo (BUF) Airport
SpartanburgFastest
FlixBus + Greyhound Lines, Inc.
Niagara Frontier Transportation Authority
SpartanburgNo tags
Greyhound Lines, Inc. + FlixBus
Niagara Frontier Transportation Authority
SpartanburgNo tags
FlixBus + Greyhound Lines, Inc.
Buffalo (BUF) Airport
SpartanburgNo tags

Last refresh of the prices: Last Friday at 15:26 EDT.

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Compare 2 ways to travel from Buffalo to Spartanburg

Bus
Average priceUS$72 - US$266Average duration1d 4h
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$236 - US$422Average duration23h 46m
84kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Buffalo to Spartanburg

Among the sustainable travel choices, the train stands out as a good way to reach Spartanburg. The journey takes about 23 hours 46 minutes and with fares starting at just US$236, it presents an excellent value for a comfortable ride.

2train per day
23h 46mAverage duration
US$236Cheapest ticket
84kgCO₂ emissions

Bus Buffalo, NY to Spartanburg: Trip Overview

Average ticket priceUS$93
Average bus trip duration1d 4h
Number of daily buses5
Earliest bus departure07:50
Distance569 miles
Latest bus departure23:59

Buffalo to Spartanburg Bus

Busbud helps you find a bus from Buffalo to Spartanburg. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Buffalo to Spartanburg will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Spartanburg from Buffalo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Buffalo, NY - Spartanburg

  1. What's the distance between Buffalo and Spartanburg by coach?

    The distance between Buffalo and Spartanburg by coach is approximately 572 miles (923 km).

  2. What is the best way to go from Buffalo to Spartanburg without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/09
US$73
30/09
No data
Today
No data
02/10
No data
03/10
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04/10
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05/10
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06/10
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busbud logoThe cheapest trip from Buffalo, NY to Spartanburg was searched and found on 29 Sept 2025 with a price of US$73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Spartanburg as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Buffalo and Spartanburg!

Much more than a mere vehicle taking you from Buffalo to Spartanburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Buffalo to Spartanburg.

Tune out to the fine sounds of your best music playlist on your bus trip from Buffalo to Spartanburg while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Buffalo, NY to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo, NY by bus?

Bus from Spartanburg to Buffalo, NY

You can also go to Spartanburg by train

Train from Buffalo, NY to Spartanburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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