Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Jacksonville Amtrak Station | Depew Station | Cheapest | ||||
| Train | Jacksonville Amtrak Station | Depew Station | Fastest | ||||
| Train | Jacksonville Amtrak Station | Depew Station | No tags | ||||
| Train | Jacksonville Amtrak Station | Depew Station | No tags | ||||
| Train | Jacksonville Amtrak Station | Exchange Street Station | No tags |
Last refresh of the prices: Today at 11:33 AM EST.
Compare 2 ways to go from Jacksonville to Buffalo
Among the sustainable travel choices, the Bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 7 hours 10 minutes, and with fares starting at just $178, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Jacksonville, FL and Buffalo, NY?
Train companies
Based on 5751 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at $301
Frequently asked questions about travelling from Jacksonville, FL to Buffalo, NY by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Jacksonville to Buffalo?
The cheapest train tickets from Jacksonville to Buffalo start at $301. The average price for this train route is around $490. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Jacksonville to Buffalo?
The average train trip from Jacksonville to Buffalo takes 1d 5h and covers 1420 km. The quickest train gets you there in 1d 4h and is operated by Amtrak.
Which train operators serve the Jacksonville to Buffalo route?
Several major train operators serve this route, with 2 trains available per day.
What are the earliest and latest departure times for the train from Jacksonville to Buffalo?
The earliest train from Jacksonville to Buffalo departs at 4:11pm. The latest train departs at 5:11pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Buffalo, NY was searched and found on Jan 29, 2026 with a price of $378To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville, FL to Buffalo, NY, as early as possible.
You can expect to pay from $378 to $3,038 for a train ticket from Jacksonville, FL to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $378 which is on 2026-01-29.
