Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Omnibus Rosario | Terminal de Ómnibus de Santiago del Estero | Cheapest | ||||
 | Bus | Terminal de Omnibus Rosario | Terminal Malbran | Fastest | ||||
| Bus | Terminal de Omnibus Rosario | Terminal de Ómnibus de Santiago del Estero | No tags | ||||
 | Bus | Terminal de Omnibus Rosario | Terminal de Ómnibus de Santiago del Estero | No tags | ||||
 | Bus | Terminal de Omnibus Rosario | Terminal de Ómnibus de Santiago del Estero | No tags |
Last refresh of the prices: Yesterday at 6:52 PM -03.
Get from Rosario to Santiago del Estero
The journey takes about 10 hours 10 minutes, and with fares starting at just $42, it presents an excellent value for a comfortable ride.
Where are the popular stops in Rosario and Santiago del Estero?
Stops in Rosario
- ACafferata 700-702, Rosario, Santa Fe, Argentina
- BBv. 27 de Febrero 2801, S2003HQG Rosario, Santa Fe, Argentina
- CBv. Seguí 2209, S2003CIA Rosario, Santa Fe, Argentina
- DBv. Oroño 4600, Rosario, Santa Fe, Argentina
- E
Bv. Oroño 5756
Bv. Oroño 5756, S2011LZT Rosario, Santa Fe, Argentina - F
Córdoba
Córdoba, Rosario, Santa Fe, Argentina
Stops in Santiago del Estero
- A
Terminal de Ómnibus de Santiago del Estero
Chacabuco, s/n, 4200 Santiago del Estero - BSta Fe 484, 4200 Santiago del Estero, Santiago del Estero, Argentina
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Frequently asked questions about travelling from Rosario, AR to Santiago del Estero by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rosario to Santiago del Estero?
The cheapest bus tickets from Rosario to Santiago del Estero start from $42. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rosario to Santiago del Estero?
The average bus travel time from Rosario to Santiago del Estero is 10h 10m, covering a distance of 668 km. The quickest bus can get you there in 5h 30m and is operated by Vosa.
Which bus companies service the Rosario to Santiago del Estero route?
Several major bus companies operate on this route with 12 buses available per day, including services from Flechabus, Vosa, Balut, Via Tac, La Veloz del Norte, 20 de Junio, Almirante Brown / Brown, Via Bariloche, Rápido Tata, Acuerdo Comercial de Salta, Chevallier.
What are the earliest and latest departure times for the bus from Rosario to Santiago del Estero?
The earliest bus departs from Rosario to Santiago del Estero at 12:10am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Rosario to Santiago del Estero?
A bus trip from Rosario to Santiago del Estero generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rosario to Santiago del Estero?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 585 reviews.
Which bus company has the best Wi-Fi from Rosario to Santiago del Estero?
Based on Busbud reviews, the bus company 20 de Junio has the highest Wi-Fi rating with a score of 2.3.
Which bus company has the best on-time performance from Rosario to Santiago del Estero?
According to Busbud traveller reviews, the most punctual bus company on this route is 20 de Junio, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Rosario to Santiago del Estero?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rosario, AR to Santiago del Estero was searched and found on Dec 2, 2025 with a price of $42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rosario, AR to Santiago del Estero, as early as possible.
You can expect to pay from $42 to $111 for a bus ticket from Rosario, AR to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2025-12-06.
Usually La Veloz del Norte, Via Tac will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
