Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Prague (Main Railway Station) | Wuppertal | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Wuppertal | No tags | ||||
| Bus | PRG Airport | Wuppertal | No tags | ||||
| Bus | Černý Most | Wuppertal | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Wuppertal | No tags |
Compare 3 ways to go from Prague to Wuppertal
Among the sustainable travel choices, the carpool stands out as the good way to reach Wuppertal. The journey takes about 7 hours and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Wuppertal?
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BAviatická, 161 08, Praha 6, Czechia
- CKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Wuppertal
- ABerliner Straße 206, 42277 Wuppertal
- B
Wuppertal (Bf. Oberbarmen)
Paul-Humburg-Straße 5-6, 42275 Wuppertal, Germany - CDöppersberg 35A, 42103 Wuppertal, Germany
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Prague to Wuppertal by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Wuppertal?
The cheapest bus tickets from Prague to Wuppertal start from $49. The average price for this route is around $66. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Wuppertal?
The average bus trip duration from Prague to Wuppertal is 18h 45m, covering a distance of 326 miles (526 km). The quickest bus can get you there in 13h 35m and is operated by FlixBus.
Which bus companies service the Prague to Wuppertal route?
Several major train operators operate on this route with 11 trains available per day.
What is the earliest and latest departure time for the bus from Prague to Wuppertal?
The earliest bus departs from Prague to Wuppertal at 12:10am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Prague to Wuppertal?
A bus trip from Prague to Wuppertal generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Wuppertal was searched and found on Dec 3, 2025 with a price of $45To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Wuppertal, as early as possible.
You can expect to pay from $45 to $87 for a bus ticket from Prague to Wuppertal based on the last 2 days. You can expect to find the cheapest price for the trip at $45 which is on 2025-12-03.
