Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Frederick | Panama City Beach Station | No tags | ||||
Greyhound + FlixBus | Bus | Frederick | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound | Bus | Frederick | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound | Bus | Frederick | Panama City Beach Station | No tags | ||||
Greyhound + FlixBus | Bus | Frederick | Panama City Beach Station | No tags |
Get from Frederick to Panama City
The journey takes about 1 day, 8 hours 30 minutes and with fares starting at just $278, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Frederick to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Frederick to Panama City?
The cheapest bus tickets from Frederick to Panama City start from $278. The average price for this route is around $344. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Frederick to Panama City?
The average bus trip duration from Frederick to Panama City is 1d 8h, covering a distance of 792 miles (1278 km). The quickest bus can get you there in 1d 7h and is operated by Greyhound.
Which bus companies service the Frederick to Panama City route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the bus from Frederick to Panama City?
The earliest bus departs from Frederick to Panama City at 1:05am. And the latest bus departs at 7:35pm.
What are the CO₂ emissions for the bus trip from Frederick to Panama City?
A bus trip from Frederick to Panama City generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Frederick to Panama City, US was searched and found on Nov 30, 2025 with a price of $337To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frederick to Panama City, US, as early as possible.
