How much does a bus ticket from Santiago to Penco cost?

The bus ticket price from Santiago to Penco starts at R 253. The best way to find cheap bus tickets from Santiago to Penco is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from Santiago to Penco?

The average travel time between Santiago and Penco is around 5h 6m, although the fastest bus will take about 5h 5m. This is the time it takes to travel the 429 km that separates the two cities.

How many daily bus connections are there between Santiago and Penco?

The number of buses from Santiago to Penco can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santiago to Penco by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from Santiago to Penco?

When taking the bus from Santiago to Penco, you can travel comfortably and safely with Eme Bus.

What are the departure and arrival stations when taking the bus from Santiago to Penco?

Buses travelling between Santiago and Penco leave from Terminal Sur or Terminal Los Héroes and arrive at Terminal de Autobuses de Penco.

Bus Santiago to Penco from R 221 | Refundable Tickets

Previously seen journeys

Next departures from Santiago to Penco on 14 November
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	15:00	Terminal Sur	5h 6m	20:06	Penco	No tags
Bus	17:00	Terminal Sur	5h 6m	22:06	Penco	No tags
Bus	18:30	Terminal Sur	5h 6m	23:36	Penco	No tags
Bus	23:00	Terminal Sur	5h 6m	04:06	Penco	No tags
Bus	23:30	Terminal Sur	5h 6m	04:36	Penco	No tags

Get from Santiago to Penco

This route is served by bus only

The journey takes about 5 hours 6 minutes, and with fares starting at just R 253, it presents an excellent value for a comfortable ride.

7bus per day

5h 6mAverage duration

421 kmDistance

11kgCO₂ emissions

Compare bus companies

Eme Bus

4/5157 reviews

Staff4.6

Timeliness4.4

Cleanliness4.8

WiFi2.9

Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the Wi-Fi. Eme Bus ticket prices on this trip start at R 253

CL Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Santiago and Penco?

Stops in Santiago

A - Terminal Sur

B - Terminal Los Héroes

C - San Borja

D - Terminal ETM

E - Pajaritos

F - Santiago

Stops in Penco

A - Terminal de Autobuses de Penco

Frequently asked questions about travelling from Santiago, CL to Penco by bus

How much does a bus ticket from Santiago to Penco cost?
The bus ticket price from Santiago to Penco starts at R 253. The best way to find cheap bus tickets from Santiago to Penco is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Santiago to Penco?
The average travel time between Santiago and Penco is around 5h 6m, although the fastest bus will take about 5h 5m. This is the time it takes to travel the 429 km that separates the two cities.
How many daily bus connections are there between Santiago and Penco?
The number of buses from Santiago to Penco can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santiago to Penco by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Santiago to Penco?
When taking the bus from Santiago to Penco, you can travel comfortably and safely with Eme Bus.
What are the departure and arrival stations when taking the bus from Santiago to Penco?
Buses travelling between Santiago and Penco leave from Terminal Sur or Terminal Los Héroes and arrive at Terminal de Autobuses de Penco.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/11

No data

13/11

No data

Today

No data

15/11

No data

16/11

No data

17/11

No data

18/11

No data

19/11

R 221

The cheapest trip from Santiago, CL to Penco was searched and found on 19 Nov 2025 with a price of R 221

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Penco as early as possible.

You can expect to pay from R 221 to R 321 for a bus ticket from Santiago, CL to Penco based on the last 2 days. You can expect to find the cheapest price for the trip at R 221, which is on 2025-11-19.